The effect of pain on outcomes in a trial of duloxetine treatment of major depressive disorder

LM Arnold, AL Meyers, P Sunderajan… - Annals of Clinical …, 2008 - Taylor & Francis
Background. Patients with major depressive disorder (MDD) frequently report one or more
pain symptoms. To explore the relationship between improvement in pain symptoms and …

The effect of duloxetine on painful physical symptoms in depressed patients: do improvements in these symptoms result in higher remission rates?

M Fava, CH Mallinckrodt, MJ Detke… - Journal of Clinical …, 2004 - psychiatrist.com
Background: Depression is a chronic disease consisting of emotional/psychological and
physical symptoms. Emotional symptoms have been shown to respond to currently available …

A randomized placebo-controlled trial of duloxetine in patients with major depressive disorder and associated painful physical symptoms

PJ Gaynor, M Gopal, W Zheng… - … medical research and …, 2011 - Taylor & Francis
Objective: Painful physical symptoms are common in patients with major depressive
disorder (MDD) and may predict poorer treatment outcomes. Duloxetine has demonstrated …

Duloxetine versus placebo in the treatment of major depressive disorder and associated painful physical symptoms: a replication study

PJ Gaynor, M Gopal, W Zheng… - … medical research and …, 2011 - Taylor & Francis
Objective: Painful physical symptoms are common in patients with major depressive
disorder (MDD) and can negatively affect patient outcomes. Duloxetine has demonstrated …

Relationship between major depressive disorder and associated painful physical symptoms: analysis of data from two pooled placebo-controlled, randomized studies …

MJ Robinson, D Sheehan, PJ Gaynor… - International clinical …, 2013 - journals.lww.com
The aim of this study was to evaluate the relationship between painful physical symptoms
(PPS) and outcomes in major depressive disorder (MDD). Post-hoc analysis of two …

Predictors of relapse in a study of duloxetine treatment in patients with major depressive disorder

M Fava, C Wiltse, D Walker, S Brecht, A Chen… - Journal of affective …, 2009 - Elsevier
BACKGROUND: Using data from a relapse prevention study of duloxetine treatment for
adults with major depressive disorder (MDD), we examined demographic-and illness …

Efficacy and safety of duloxetine 60 mg once daily in the treatment of pain in patients with major depressive disorder and at least moderate pain of unknown etiology: a …

S Brecht, C Courtecuisse, C Debieuvre… - Journal of Clinical …, 2007 - psychiatrist.com
Objective: Experience of pain in major depressive disorder (MDD) can complicate diagnosis
and impair treatment outcomes. This study evaluated the efficacy and safety of duloxetine in …

[HTML][HTML] Efficacy and safety of duloxetine 60 mg once daily in major depressive disorder: a review with expert commentary

SG Ball, D Desaiah, Q Zhang, ME Thase… - Drugs in …, 2013 - ncbi.nlm.nih.gov
Objective: Major depressive disorder (MDD) is a significant public health concern and
challenges health care providers to intervene with appropriate treatment. This article …

Predictors of remission in the treatment of major depressive disorder: real-world evidence from a 6-month prospective observational study

D Novick, J Hong, W Montgomery… - Neuropsychiatric …, 2015 - Taylor & Francis
Background This study examined potential predictors of remission among patients treated
for major depressive disorder (MDD) in a naturalistic clinical setting, mostly in the Middle …

Time course of depression‐symptom improvement during treatment with duloxetine

RMA Hirschfeld, C Mallinckrodt, TC Lee… - Depression and …, 2005 - Wiley Online Library
The aim of this study was to examine the longitudinal response for overall and individual
symptoms during the treatment of major depressive disorder. Data were pooled from two 9 …