Glaucoma is a multifactorial progressive optic neuropathy whose main risk factor is
intraocular hypertension (IOH). It generates loss of nerves and is the primary cause of …

Glaucoma is a multifactorial progressive optic neuropathy whose main risk factor is
intraocular hypertension (IOH). It generates loss of nerves and is the primary cause of …

Glaucoma is a neurodegenerative disease characterized by the progressive loss of retinal
ganglion cells (RGC s). Elevated intraocular pressure (IOP) is a primary risk factor for the …

Glaucoma is a common complex disease that leads to irreversible blindness worldwide.
Even though preclinical studies showed that lowering intraocular pressure (IOP) could …

Introduction: Rodents have widely been used to represent glaucomatous changes both in
the presence and absence of elevated intraocular pressure (IOP) as they offer clear …

Glaucoma is a neurodegenerative disease characterized by visual field loss associated with
optic nerve damage and ocular hypertension. The biological basis for the elevated …

This chapter provides an overview over the use of animal models in glaucoma research from
a historical perspective. Strengths and limitations of various models are considered, and the …

Glaucoma, a leading cause of blindness worldwide, is a degenerative disease characterized
by retinal ganglion cell (RGC) loss and optic nerve atrophy. Elevated intraocular pressure …

Purpose: To compare four different animal models of chronic glaucoma with normal ageing
over 6 months. Methods: Chronic glaucoma was induced in 138 Long‐Evans rats and …

Introduction: In vivo screening studies, in which the efficacy of dozens of drugs is tested to
select several applicants for further study of their safety in humans, are the main stage in the …