As the 5-hydroxytryptamine6 (5-HT6) receptor is almost exclusively expressed in the CNS,
particularly in areas associated with learning and memory, many studies have examined its …

The hippocampus is a major limbic target of the brainstem serotonergic neurons that
modulate fear, anxiety, and learning through postsynaptic serotonin1A receptors (5-HT1A …

5-ht6 receptors are the latest serotonin receptors to be identified by molecular cloning. Their
high affinity for a wide range of drugs used in psychiatry, coupled with their intriguing …

The study of 5-hydroxytryptamine (5-HT) system has benefited from the identification,
classification and cloning of multiple 5-HT receptors (5-HT1 to 5-HT7). Growing evidence …

Evidence from invertebrates to human studies indicates that serotonin (5-hydroxytryptamine;
5-HT) system modulates short-(STM) and long-term memory (LTM). This work is primarily …

Serotonin receptors 5-HT1A and 5-HT7 are highly coexpressed in brain regions implicated
in depression. However, their functional interaction has not been established. In the present …

BACKGROUND AND PURPOSE 5‐HT6 receptors are abundant in the hippocampus,
nucleus accumbens and striatum, supporting their role in learning and memory. Selective 5 …

The consequences of the absence of 5-HT reuptake on the functional properties of 5-HT1A
receptors were examined in the dorsal raphe nucleus and the hippocampus of knock-out …

Serotonin (5-HT) is a neurotransmitter that plays an important role in neuronal plasticity.
Variations in the levels of 5-HT at the synaptic cleft, expression or dysfunction of 5-HT …

Reductions in function within the serotonin (5HT) neuronal system have long been proposed
as etiological factors in depression. Selective serotonin reuptake inhibitors (SSRIs) are the …