Four epidemiologic studies showed a twofold increase in risk of deep venous thrombosis
with the use of oral contraceptives containing third-generation progestins, relative to second …

Recent data indicate that users of third-generation oral contraceptives, those containing the
new progestins desogestrel, gestodene, and norgestimate, have 2 to 3 times the risk of …

Objective: The object of the study was to determine the effects of oral contraceptives on
blood coagulation, in particular on the protein C pathway. Study Design: Plasma samples …

Objective: To evaluate quantitatively articles that compared effects of second and third
generation oral contraceptives on risk of venous thrombosis. Design: Meta-analysis. Studies …

An increased risk of venous thrombosis has been demonstrated in women receiving oral
contraceptives (OCs). This risk has been primarily associated with the oestrogen content, but …

4. Koster T, Rosendaal FR, de Ronde H, Briet E, Vandenbroucke JP, Bertina RM. Venous
thrombosis due to poor anticoagulant response to activated protein C: Leiden thrombophilia …

Recent concern about the safety of combined oral contraceptives (OCs) with third-
generation progestagens prompted an examination of data from a population-based case …

Late in 1995 and early 1996, 4 epidemiologic studies were published that resulted in a
crude mean weighted relative risk of approximately 2 when third-generation oral …

Compared to second generation, the use of third generation oral contraceptives has been
associated with an increased risk of venous thrombosis especially in women with the factor …

Background Major concern was raised by an earlier study regarding oral contraceptive use
in women with the factor V Leiden mutation. A more than 30-fold increase in relative risk for …