Shear stress protects against endothelial regulation of vascular smooth muscle cell migration in a coculture system

HQ Wang, LX Huang, MJ Qu, ZQ Yan, B Liu… - Endothelium, 2006 - Taylor & Francis
Vascular endothelial cells (ECs) are constantly exposed to blood flow–induced shear stress;
these forces strongly influence the behaviors of neighboring vascular smooth muscle cells …

Shear stress inhibits adhesion molecule expression in vascular endothelial cells induced by coculture with smooth muscle cells

JJ Chiu, LJ Chen, PL Lee, CI Lee, LW Lo… - Blood, The Journal …, 2003 - ashpublications.org
Vascular endothelial cells (ECs), which exist in close proximity to vascular smooth muscle
cells (SMCs), are constantly subjected to blood flow–induced shear stress. Although the …

Normal shear stress and vascular smooth muscle cells modulate migration of endothelial cells through histone deacetylase 6 activation and tubulin acetylation

YH Wang, ZQ Yan, YX Qi, BB Cheng, XD Wang… - Annals of biomedical …, 2010 - Springer
Endothelial cells (ECs) line the innermost of the blood vessel wall and are constantly
subjected to shear stress imposed by blood flow. ECs were also influenced by the …

A model for studying the effect of shear stress on interactions between vascular endothelial cells and smooth muscle cells

JJ Chiu, LJ Chen, CN Chen, PL Lee, CI Lee - Journal of biomechanics, 2004 - Elsevier
Vascular endothelial cells (ECs) are constantly subjected to blood flow-induced shear stress
and the influences of neighboring smooth muscle cells (SMCs). In the present study, a …

[HTML][HTML] SIRT1 and Connexin40 Mediate the normal shear stress-induced inhibition of the proliferation of endothelial cells co-cultured with vascular smooth muscle …

QP Yao, YX Qi, P Zhang, BB Cheng, ZQ Yan… - Cellular physiology and …, 2013 - karger.com
Background: Shear stress imposed by blood flow directly impacts endothelial cells (ECs),
which are simultaneously influenced by neighboring vascular smooth muscle cells (VSMCs) …

Shear stress activates Akt during vascular smooth muscle cell reorientation

KM Rice, SK Kakarla, SP Mupparaju… - Biotechnology and …, 2010 - Wiley Online Library
Vascular intervention procedures can lead to endothelial damage and expose the
underlying VSMCs (vascular smooth muscle cells) to shear stress. Although shear stress …

Shear stress and vascular smooth muscle cells promote endothelial differentiation of endothelial progenitor cells via activation of Akt

C Ye, L Bai, ZQ Yan, YH Wang, ZL Jiang - Clinical Biomechanics, 2008 - Elsevier
BACKGROUND: The structural and functional integrity of endothelium plays a pivotal role in
the pathogenesis of cardiovascular diseases. Endothelial progenitor cells (EPCs) is a …

Effect of fluid shear stress on migration of vascular smooth muscle cells in cocultured model

N Sakamoto, T Ohashi, M Sato - Annals of biomedical engineering, 2006 - Springer
Migration of smooth muscle cells (SMCs) in hyperplasia is thought to have a correlation with
blood flow conditions. In this study, the effect of shear stress applied to endothelial cells …

Role of blood shear stress in the regulation of vascular smooth muscle cell migration

SQ Liu, J Goldman - IEEE transactions on biomedical …, 2001 - ieeexplore.ieee.org
Smooth muscle cell (SMC) migration from the media to the intima of blood vessels
contributes to neointimal formation and atherogenesis. Here, the authors demonstrate how …

Shear stress inhibits smooth muscle cell migration via nitric oxide-mediated downregulation of matrix metalloproteinase-2 activity

JS Garanich, M Pahakis… - American Journal of …, 2005 - journals.physiology.org
Vascular smooth muscle cell (SMC) migration is a hallmark of intimal hyperplasia (IH), the
progression of which is affected by hemodynamic conditions at the diseased site. The …