miR-323a regulates ERBB4 and is involved in depression

LM Fiori, A Kos, R Lin, JF Théroux, JP Lopez… - Molecular …, 2021 - nature.com
Major depressive disorder (MDD) is a complex and debilitating illness whose etiology
remains unclear. Small RNA molecules, such as micro RNAs (miRNAs) have been …

Circulating microRNAs as biomarkers for depression: many candidates, few finalists

H Yuan, D Mischoulon, M Fava, MW Otto - Journal of affective disorders, 2018 - Elsevier
Background Recent research has highlighted the potential of microRNAs to serve as
physiological indicators of disease process among clinically depressed patients. Methods In …

Exploiting circulating MicroRNAs as biomarkers in psychiatric disorders

B Roy, Y Yoshino, L Allen, K Prall, G Schell… - Molecular diagnosis & …, 2020 - Springer
Non-invasive peripheral biomarkers play a significant role in both disease diagnosis and
progression. In the past few years, microRNA (miRNA) expression changes in circulating …

Comparison of plasma MicroRNA levels in drug naive, first episode depressed patients and healthy controls

MA Camkurt, Ş Acar, S Coşkun, M Güneş… - Journal of psychiatric …, 2015 - Elsevier
Major depression is the most common psychiatric disorder. The diagnosis of depression
depends on a patient's subjective complaints, and the nature of the heterogeneous disorder …

Pathogenetic and therapeutic applications of microRNAs in major depressive disorder

Y Dwivedi - Progress in Neuro-Psychopharmacology and …, 2016 - Elsevier
As a class of noncoding RNAs, microRNAs (miRNAs) regulate gene expression by inhibiting
translation of messenger RNAs. These miRNAs have been shown to play a critical role in …

Amygdala-based altered miRNome and epigenetic contribution of miR-128-3p in conferring susceptibility to depression-like behavior via Wnt signaling

B Roy, M Dunbar, J Agrawal, L Allen… - International Journal of …, 2020 - academic.oup.com
Background Recent studies suggest that microRNAs (miRNAs) can participate in depression
pathogenesis by altering a host of genes that are critical in corticolimbic functioning. The …

Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression

RM O'connor, TG Dinan, JF Cryan - Molecular psychiatry, 2012 - nature.com
Anxiety and depression are devastating mental illnesses that are a significant public health
concern. Selective serotonin-reuptake inhibitors are the first-line treatment strategy for these …

Hippocampal miR-211-5p regulates neurogenesis and depression-like behaviors in the rat

Y Li, C Fan, R Gao, T Lan, W Wang, SY Yu - Neuropharmacology, 2021 - Elsevier
Emerging evidence has shown that microRNAs (miRNAs) contribute to the pathogenesis of
depression, a potentially life-threatening and disabling mental disorder caused by the …

MicroRNA expression is down-regulated and reorganized in prefrontal cortex of depressed suicide subjects

NR Smalheiser, G Lugli, HS Rizavi, VI Torvik… - PloS one, 2012 - journals.plos.org
Background Recent studies suggest that alterations in expression of genes, including those
which regulate neural and structural plasticity, may be crucial in the pathogenesis of …

Blood microRNA changes in depressed patients during antidepressant treatment

L Bocchio-Chiavetto, E Maffioletti, P Bettinsoli… - European …, 2013 - Elsevier
MicroRNAs (miRNAs) are potent modulators of protein expression that play key roles in
brain pathways regulating neurogenesis and synaptic plasticity. These small RNAs may be …