Major depressive disorder (MDD) is a serious and common psychiatric disorder that affects
millions of people worldwide. The most common treatment methods for MDD are …

Exposure to acute traumatic stress can cause permanent changes in neurological circuitry
and may lead to the development of an anxiety disorder known as posttraumatic stress …

Stress response refers to the systemic nonspecific response upon exposure to strong
stimulation or chronic stress, such as severe trauma, shock, infection, burn, major surgery or …

Late-life depression is associated with an increased risk for dementia but we have limited
knowledge of the molecular mechanisms underlying this association. Here we investigated …

Aberrant expression of microRNAs (miRNAs) has been shown to be involved in early
observations of depression. The aim of this study was to determine if serum levels of miRNA …

Mood disorders are the most prevalent psychiatric disorders associated with significant
disability, morbidity, and mortality. The risk of suicide is associated with severe or mixed …

Stress research has progressively become more integrative in nature, seeking to unfold
crucial relations between the different phenotypic levels of stress manifestations. This study …

Because of the role played by miRNAs in post-transcriptional regulation of an array of
genes, their impact in neuropsychiatric disease pathophysiology has increasingly been …

Background MicroRNAs (miRs) have been suggested to be biomarkers to inform the
diagnosis of major depressive disorder (MDD). We have previously shown that exosome …

To date, it remains impossible to guarantee that short-term treatment given to a patient
suffering from a major depressive episode (MDE) will improve long-term efficacy. Objective …