Dehydration: a new alcohol theory

WR Klemm - Alcohol, 1990 - Elsevier
A central belief about ethanol is that it acts mainly by partitioning into the lipid bilayer of
membranes. Newer ideas focus on the neuronal synapse and suggest that ethanol can …

Glucose and lactate supply to the synapse

LF Barros, JW Deitmer - Brain research reviews, 2010 - Elsevier
The main source of energy for the mammalian brain is glucose, and the main sink of energy
in the mammalian brain is the neuron, so the conventional view of brain energy metabolism …

Carbohydrate-mediated biomolecular recognition and gating of synthetic ion channels

M Ali, S Nasir, P Ramirez, J Cervera… - The Journal of …, 2013 - ACS Publications
Nanochannel-based biosensing devices have been proposed for selective detection of
protein analyte molecules. However, the design and miniaturization of reusable channel …

Spatial dynamics of the insulin receptor in living neurons

M Gralle, S Labrecque, C Salesse… - Journal of …, 2021 - Wiley Online Library
Insulin signaling through the insulin receptor has long been studied in classic target organs,
such as adipose tissue and skeletal muscle, where one of its effects is to increase glucose …

Reconstitution of lysosomal ion channels into artificial membranes

E Venturi, R Sitsapesan - Methods in Cell Biology, 2015 - Elsevier
Ion channels that are located on intracellular organelles have always posed challenges for
biophysicists seeking to measure their ion conduction, selectivity, and gating kinetics. Unlike …

Fundamentals of physico-chemistry of glycolipids in membranes

CWM Grant - Gangliosides and modulation of neuronal functions, 1987 - Springer
Physical aspects of glycolipids in membranes are of interest because physical factors may
have important bearing on their structural and receptor roles. However certain points remain …

Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation

Y Izumi, AM Benz, H Katsuki… - Journal of …, 1997 - Soc Neuroscience
The ability to fuel neurons via glycogenolysis is believed to be an important function of glia.
Indeed, the slow, rather than immediate, depression of synaptic transmission in …

Perspectives and functional implications

RU Margolis, RK Margolis - Complex carbohydrates of nervous tissue, 1979 - Springer
Although the preceding chapters have summarized much of our current knowledge
regarding nervous tissue complex carbohydrates, it is evident that most hypotheses …

Lipid rafts are involved in C95 (4, 8) agrin fragment-induced acetylcholine receptor clustering

JA Campagna, J Fallon - Neuroscience, 2006 - Elsevier
During development of the neuromuscular junction, high densities of acetylcholine receptors
accumulate beneath the overlying nerve terminal. A defining feature of mature synapses is …

Cholesterol depletion from the plasma membrane impairs proton and glutamate storage in synaptic vesicles of nerve terminals

AS Tarasenko, RV Sivko, NV Krisanova… - Journal of molecular …, 2010 - Springer
We report that cholesterol depletion with methyl-β-cyclodextrin (MβCD) acutely applied to rat
brain synaptosomes is accompanied by an immediate increase in transporter-mediated …