Evolution of cyclin-dependent kinases (CDKs) and CDK-activating kinases (CAKs): differential conservation of CAKs in yeast and metazoa
J Liu, ET Kipreos - Molecular biology and evolution, 2000 - academic.oup.com
Cyclin-dependent kinases (CDKs) function as central regulators of both the cell cycle and
transcription. CDK activation depends on phosphorylation by a CDK-activating kinase …
transcription. CDK activation depends on phosphorylation by a CDK-activating kinase …
[HTML][HTML] Fission yeast Csk1 is a CAK‐activating kinase (CAKAK)
D Hermand, A Pihlak, T Westerling, V Damagnez… - The EMBO …, 1998 - embopress.org
Cell cycle progression is dependent on the sequential activity of cyclin‐dependent kinases
(CDKs). For full activity, CDKs require an activating phosphorylation of a conserved residue …
(CDKs). For full activity, CDKs require an activating phosphorylation of a conserved residue …
[HTML][HTML] Cell cycle: will the real Cdk-activating kinase please stand up
GF Draetta - Current Biology, 1997 - cell.com
Activation of a cyclin-dependent kinase (Cdk) requires its association with a cyclin subunit
and phosphorylation on a conserved residue by the Cdk-activating kinase (CAK). The …
and phosphorylation on a conserved residue by the Cdk-activating kinase (CAK). The …
The cdk-activating kinase (CAK): from yeast to mammals
P Kaldis - Cellular and Molecular Life Sciences CMLS, 1999 - Springer
Cell cycle progression is regulated by cyclin-dependent kinases (cdks). The activity of cdks
is tightly controlled by several mechanisms, including binding of subunits to cdks (cyclins …
is tightly controlled by several mechanisms, including binding of subunits to cdks (cyclins …
[HTML][HTML] Comparison of Cak1p-like cyclin-dependent kinase-activating kinases
V Tsakraklides, MJ Solomon - Journal of Biological Chemistry, 2002 - ASBMB
Cyclin-dependent kinases (cdks) coordinate progression through the eukaryotic cell cycle
and require phosphorylation by a cdk-activating kinase (CAK) for full activity. In most …
and require phosphorylation by a cdk-activating kinase (CAK) for full activity. In most …
[HTML][HTML] Specificity of Cdk activation in vivo by the two Caks Mcs6 and Csk1 in fission yeast
D Hermand, T Westerling, A Pihlak, JY Thuret… - The EMBO …, 2001 - embopress.org
Activating phosphorylation of cyclin‐dependent kinases (Cdks) is mediated by at least two
structurally distinct types of Cdk‐activating kinases (Caks): the trimeric Cdk7–cyclin H–Mat1 …
structurally distinct types of Cdk‐activating kinases (Caks): the trimeric Cdk7–cyclin H–Mat1 …
[HTML][HTML] The Cdk-activating kinase (CAK) from budding yeast
P Kaldis, A Sutton, MJ Solomon - Cell, 1996 - cell.com
Activation of the cyclin-dependent kinases to promote cell cycle progression requires their
association with cyclins as well as phosphorylation of a threonine (residue 161 in human …
association with cyclins as well as phosphorylation of a threonine (residue 161 in human …
Human and yeast cdk-activating kinases (CAKs) display distinct substrate specificities
P Kaldis, AA Russo, HS Chou… - Molecular biology of …, 1998 - Am Soc Cell Biol
Cell cycle progression is controlled by the sequential functions of cyclin-dependent kinases
(cdks). Cdk activation requires phosphorylation of a key residue (on sites equivalent to Thr …
(cdks). Cdk activation requires phosphorylation of a key residue (on sites equivalent to Thr …
Cyclin dependent kinase activating kinases
RA Sclafani - Current opinion in cell biology, 1996 - Elsevier
The cyclin dependent kinase activating kinase (CAK) has roles in both cell cycle regulation
and transcription. CAK assembly is regulated either by additional protein binding or by …
and transcription. CAK assembly is regulated either by additional protein binding or by …
[HTML][HTML] A CDK-activating kinase network is required in cell cycle control and transcription in fission yeast
JE Saiz, RP Fisher - Current Biology, 2002 - cell.com
Cyclin-dependent kinases (CDKs) involved in cell cycle control require activation by
phosphorylation, but CDK-activating kinase (CAK) has diverged between metazoans and …
phosphorylation, but CDK-activating kinase (CAK) has diverged between metazoans and …