Apolipoprotein [a] genotype influences isoform dominance pattern differently in African Americans and Caucasians
J Rubin, F Paultre, CH Tuck, S Holleran, RG Reed… - Journal of lipid …, 2002 - ASBMB
Abstract Plasma lipoprotein [a](Lp [a]) concentrations are inversely associated with, and
largely determined by, apolipoprotein [a](apo [a]) gene size, a highly polymorphic trait. We …
largely determined by, apolipoprotein [a](apo [a]) gene size, a highly polymorphic trait. We …
The apolipoprotein (a) gene: linkage disequilibria at three loci differs in African Americans and Caucasians
J Rubin, HJ Kim, TA Pearson, S Holleran, L Berglund… - Atherosclerosis, 2008 - Elsevier
Lipoprotein (a)(Lp (a)) is an independent, genetically regulated cardiovascular risk factor. Lp
(a) plasma levels are largely determined by the apolipoprotein (a)(apo (a)) component, and …
(a) plasma levels are largely determined by the apolipoprotein (a)(apo (a)) component, and …
Apo [a] size and PNR explain African American-Caucasian differences in allele-specific apo [a] levels for small but not large apo [a]
J Rubin, HJ Kim, TA Pearson, S Holleran… - Journal of lipid …, 2006 - ASBMB
Apolipoprotein [a](apo [a]) gene size is a major predictor of lipoprotein [a] level. To
determine genetic predictors of allele-specific apo [a] levels beyond gene size, we evaluated …
determine genetic predictors of allele-specific apo [a] levels beyond gene size, we evaluated …
Heritability of apolipoprotein (a) traits in two-generational African-American and Caucasian families [S]
B Enkhmaa, E Anuurad, W Zhang, K Kim… - Journal of lipid …, 2019 - ASBMB
Heritability of LPA allele, apo (a) isoform sizes, and isoform-associated lipoprotein (a)[Lp (a)]
levels was studied in 82 Caucasian and African-American families with two parents and two …
levels was studied in 82 Caucasian and African-American families with two parents and two …
Genetic basis for multimodal relationship between apolipoprotein (a) size and lipoprotein (a) concentration in Mexican-Americans
DL Rainwater - Atherosclerosis, 1995 - Elsevier
The reported general inverse relationship between apolipoprotein (a)(apo (a)) size and
plasma lipoprotein (a)(Lp (a)) concentrations was further characterized using 927 samples …
plasma lipoprotein (a)(Lp (a)) concentrations was further characterized using 927 samples …
Effects of the apolipoprotein (a) size polymorphism on the lipoprotein (a) concentration in 7 ethnic groups
C Sandholzer, DM Hallman, N Saha, G Sigurdsson… - Human genetics, 1991 - Springer
Summary Apolipoprotein (a)[apo (a)] exhibits a genetic size polymorphism explaining about
40% of the variability in lipoprotein (a)[Lp (a)] concentration in Tyroleans. Lp (a) …
40% of the variability in lipoprotein (a)[Lp (a)] concentration in Tyroleans. Lp (a) …
High degree of genetic polymorphism in apolipoprotein (a) associated with plasma lipoprotein (a) levels in Japanese and Chinese populations
S Kikuchi, A Nakagawa, K Kobayashi, L Li, H Yanagi… - Human genetics, 1993 - Springer
We have developed a sensitve, high-resolution method for the analysis of the apolipoprotein
(a)[apo (a)] isoforms using sodium dodecyl sulfate (SDS)-agarose/gradient polyacrylamide …
(a)[apo (a)] isoforms using sodium dodecyl sulfate (SDS)-agarose/gradient polyacrylamide …
Significant impact of the+ 93 C/T polymorphism in the apolipoprotein (a) gene on Lp (a) concentrations in Africans but not in Caucasians: confounding effect of linkage …
HG Kraft, M Windegger, HJ Menzel… - Human molecular …, 1998 - academic.oup.com
Abstract Lipoprotein (a)[Lp (a)] is a quantitative genetic trait in human plasma associated
with atherothrombotic disease. The major determinant of Lp (a) concentration is the …
with atherothrombotic disease. The major determinant of Lp (a) concentration is the …
Contribution of the apo [a] phenotype to plasma Lp [a] concentrations shows considerable ethnic variation.
Apolipoprotein [a] polymorphism has been investigated by sodium dodecyl sulfate
polyacrylamide (5.37%) gel electrophoresis and immunoblotting using a standardized …
polyacrylamide (5.37%) gel electrophoresis and immunoblotting using a standardized …
Hypervariable polymorphism of APO (a) in blacks and whites as reflected by phenotyping
MI Kamboh, CM Svitko, ER Williams, RE Ferrell… - Chemistry and physics …, 1994 - Elsevier
Genetic polymorphism at the apolipoprotein (a) structural locus was investigated in 203
American blacks using a high-resolution SDS-agarose electrophoresis method followed by …
American blacks using a high-resolution SDS-agarose electrophoresis method followed by …