Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis

R Sultana, M Perluigi, DA Butterfield - Acta neuropathologica, 2009 - Springer
Oxidative stress has been implicated in the pathogenesis of a number of diseases including
Alzheimer's disease (AD). The oxidative stress hypothesis of AD pathogenesis, in part, is …

Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: insights into the progression of this …

DA Butterfield, R Sultana - Journal of Alzheimer's Disease, 2007 - content.iospress.com
Alzheimer disease is a common age-related neurodegenerative disease characterized
pathologically by senile plaques, neurofibrillary tangles, synaptic disruption, and …

Roles of amyloid β-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment

DA Butterfield, T Reed, SF Newman… - Free Radical Biology and …, 2007 - Elsevier
Oxidative stress has been implicated to play a crucial role in the pathogenesis of a number
of diseases, including neurodegenerative disorders, cancer, and ischemia, just to name a …

Oxidative stress, amyloid-β peptide, and altered key molecular pathways in the pathogenesis and progression of Alzheimer's disease

DA Butterfield, D Boyd-Kimball - Journal of Alzheimer's …, 2018 - content.iospress.com
Oxidative stress is implicated in the pathogenesis and progression of Alzheimer's disease
(AD) and its earlier stage, amnestic mild cognitive impairment (aMCI). One source of …

Oxidative stress in Alzheimer disease and mild cognitive impairment: evidence from human data provided by redox proteomics

AM Swomley, DA Butterfield - Archives of toxicology, 2015 - Springer
Alzheimer disease (AD) is a neurodegenerative disease with many known pathological
features, yet there is still much debate into the exact cause and mechanisms for progression …

Oxidative modification of brain proteins in Alzheimer's disease: perspective on future studies based on results of redox proteomics studies

R Sultana, DA Butterfield - Journal of Alzheimer's Disease, 2013 - content.iospress.com
Aging is the major risk factor associated with neurodegenerative diseases, including
Alzheimer's disease (AD). Until now no clear understanding of the mechanisms of initiation …

Redox proteomics identification of oxidatively modified proteins in Alzheimer's disease brain and in vivo and in vitro models of AD centered around Aβ (1–42)

R Sultana, M Perluigi, DA Butterfield - Journal of Chromatography B, 2006 - Elsevier
Alzheimer's disease is a progressive neurodegenerative disease associated with loss of
memory and cognition. One hallmark of AD is the accumulation of amyloid β-peptide (Aβ) …

Role of oxidative stress in the progression of Alzheimer's disease

R Sultana, DA Butterfield - Journal of Alzheimer's Disease, 2010 - content.iospress.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized
pathologically by the presence of senile plaques, neurofibrillary tangles, and synapse loss …

Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain

DA Butterfield - Brain research, 2004 - Elsevier
In Alzheimer's disease (AD) brain oxidative stress is observed indexed by several markers,
among which are protein carbonyls and 3-nitrotyrosine, markers for protein oxidation. We …

Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical …

R Sultana, D Boyd-Kimball, HF Poon, J Cai… - Neurobiology of …, 2006 - Elsevier
Alzheimer's disease (AD) is characterized by the presence of neurofibrillary tangles, senile
plaques and loss of synapses. There is accumulating evidence that oxidative stress plays an …