The prognostic significance of cerebrospinal fluid in multiple sclerosis

S Siritho, MS Freedman - Journal of the neurological sciences, 2009 - Elsevier
BACKGROUND: Multiple Sclerosis (MS) patients lacking CSF oligoclonal bands are
purported to have a milder course of disease. We reviewed the natural history of oligoclonal …

The clinical significance of an intrathecal monoclonal immunoglobulin band: a follow-up study

G Davies, G Keir, EJ Thompson, G Giovannoni - Neurology, 2003 - AAN Enterprises
Background: Intrathecal oligoclonal band synthesis occurs in 95% of patients with clinically
definite MS but may also occur in the context of CNS infection and other inflammatory …

Oligoclonal bands and cerebrospinal fluid markers in multiple sclerosis: associations with disease course and progression

P Lourenco, A Shirani, J Saeedi, J Oger… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: The use of oligoclonal bands (OCBs) and cerebrospinal fluid (CSF) parameters
are established in the diagnosis of MS, but poorly as markers of disease. Objective: To …

Cerebrospinal fluid immunological biomarkers associated with axonal damage in multiple sclerosis

LM Villar, C Picón, L Costa‐Frossard… - European journal of …, 2015 - Wiley Online Library
Background and purpose Cerebrospinal fluid (CSF) neurofilament light protein (NFL) is a
promising biomarker of axonal injury and neurodegeneration. Here CSF lymphocyte …

Antimyelin antibodies in clinically isolated syndromes correlate with inflammation in MRI and CSF

J Kuhle, RLP Lindberg, A Regeniter, M Mehling… - Journal of …, 2007 - Springer
Objective We investigated the correlation of anti-myelin oligodendrocyte glycoprotein-(anti-
MOG) and anti-myelin basic protein antibodies (anti-MBP) in serum of CIS patients with …

Cerebrospinal fluid

T Olsson - Annals of Neurology: Official Journal of the …, 1994 - Wiley Online Library
Examination of cerebrospinal fluid (CSF) in the context of multiple sclerosis (MS), is valuable
for several reasons. First, routine diagnostic evaluation of CSF cell counts and various forms …

Myelin basic protein in CSF as indicator of disease activity in multiple sclerosis

KJB Lamers, HPM de Reus… - Multiple Sclerosis …, 1998 - journals.sagepub.com
There is an evident need for a quantitative laboratory marker for ascertaining disease activity
and treatment effects in multiple sclerosis (MS) patients. Activity of the disease process in …

Absence of cerebrospinal fluid oligoclonal bands is associated with delayed disability progression in relapsing-remitting MS patients treated with interferon-β

P Annunziata, A Giorgio, L De Santi, V Zipoli… - Journal of the …, 2006 - Elsevier
To assess the role of CSF oligoclonal bands (OB) in determining the clinical outcome in
patients with relapsing-remitting multiple sclerosis (RRMS) treated with IFN-β, we carried out …

The use and abuse of the cerebrospinal fluid IgG profile in the adult: a practical evaluation

LA Hershey, JL Trotter - Annals of Neurology: Official Journal of …, 1980 - Wiley Online Library
Cerebrospinal fluid (CSF) samples from 150 patients with multiple sclerosis (MS) and 190
patients with other neurological disorders were examined with a battery of tests (the IgG …

Urinary myelin basic protein—like material as a correlate of the progression of multiple sclerosis

JN Whitaker, RD Kachelhofer… - Annals of Neurology …, 1995 - Wiley Online Library
In the multicenter, randomized, placebo‐controlled trial of alternate‐day injections of
recombinant interferon beta‐1b in relapsing‐remitting multiple sclerosis (MS), urine …