Influence of process parameters on tablet bed microenvironmental factors during pan coating
P Pandey, DS Bindra, LA Felton - Aaps Pharmscitech, 2014 - Springer
Recent studies have shown the importance of monitoring microenvironmental conditions
(temperature, relative humidity) experienced by the tablet bed during a pan coating process …
(temperature, relative humidity) experienced by the tablet bed during a pan coating process …
Real‐time monitoring of thermodynamic microenvironment in a pan coater
P Pandey, DS Bindra - Journal of pharmaceutical sciences, 2013 - Wiley Online Library
The current study demonstrates the use of tablet‐size data logging devices (PyroButtons) to
quantify the microenvironment experienced by tablets during pan coating process …
quantify the microenvironment experienced by tablets during pan coating process …
Correlating bilayer tablet delamination tendencies to micro-environmental thermodynamic conditions during pan coating
BM Zacour, P Pandey, G Subramanian… - Drug Development …, 2014 - Taylor & Francis
Objective: The objective of this study was to determine the impact that the micro-
environment, as measured by PyroButton data loggers, experienced by tablets during the …
environment, as measured by PyroButton data loggers, experienced by tablets during the …
Understanding the thermodynamic micro-environment inside a pan coater using a data logging device
P Pandey, J Ji, G Subramanian, S Gour… - Drug Development …, 2014 - Taylor & Francis
Objective: The objective of the current study was to establish the use of PyroButton data-
logging device to monitor and quantify the thermodynamic environment (temperature and …
logging device to monitor and quantify the thermodynamic environment (temperature and …
Development of an automation system for a tablet coater
M Ruotsalainen, J Heinämäki, J Rantanen… - AAPS PharmSciTech, 2002 - Springer
An instrumentation and automation system for a side-vented pan coater with a novel air-flow
rate measurement system for monitoring the film-coating process of tablets was designed …
rate measurement system for monitoring the film-coating process of tablets was designed …
Interrelationships between coating uniformity and efficiency in pan coating processes
M Choi, SC Porter, A Meisen - AAPS PharmSciTech, 2021 - Springer
The relationships between coating uniformity and efficiency were explored for tablet coating
processes in pan coaters. The factors affecting the size of the spray zone were modeled …
processes in pan coaters. The factors affecting the size of the spray zone were modeled …
Setting the process parameters for the coating process in order to assure tablet appearance based on multivariate analysis of prior data
S Tanabe, H Nakagawa, T Watanabe, H Minami… - International journal of …, 2016 - Elsevier
Designing efficient, robust process parameters in drug product manufacturing is important to
assure a drug s critical quality attributes. In this research, an efficient, novel procedure for …
assure a drug s critical quality attributes. In this research, an efficient, novel procedure for …
Evaluation of the tablets' surface flow velocities in pan coaters
G Toschkoff, A Funke, A Altmeyer, K Knop… - European Journal of …, 2016 - Elsevier
The tablet pan coating process involves various types of transverse tablet bed motions,
ranging from rolling to cascading. To preserve satisfactory results in terms of coating quality …
ranging from rolling to cascading. To preserve satisfactory results in terms of coating quality …
Improvement of tablet coating uniformity using a quality by design approach
A Dubey, F Boukouvala, G Keyvan, R Hsia… - AAPS …, 2012 - Springer
A combination of analytical and statistical methods is used to improve a tablet coating
process guided by quality by design (QbD) principles. A solid dosage form product was …
process guided by quality by design (QbD) principles. A solid dosage form product was …
Modeling of pan coating processes: Prediction of tablet content uniformity and determination of critical process parameters
We developed an engineering model for predicting the active pharmaceutical ingredient
(API) content uniformity (CU) for a drug product in which the active is coated onto a core. The …
(API) content uniformity (CU) for a drug product in which the active is coated onto a core. The …