Objective. To investigate the effectiveness and feasibility of extracorporeal
photochemotherapy (ECP) in the treatment of an autoimmune disease with known …

Background The first reports of the application of ultravioletA1 (UVA1) phototherapy for
scleroderma go back only to 1995, but since then, several studies have proven its …

Extracorporeal photopheresis (ECP) has demonstrated therapeutic benefit in patients with
Sézary syndrome (SS) and erythrodermic mycosis fungoides (e-MF). To examine the …

Purpose: To evaluate the efficacy of medium-dose UVA1 phototherapy in patients with
localized scleroderma. Method: A controlled pilot study with medium-dose UVA1 (48 J/cm2) …

Juvenile localized scleroderma (jLS) is an orphan disease that can lead to cosmetic
disfiguration and orthopedic problems. Two recent publications review the current …

REPORT OF A CASE A 42-year-old woman who suffered for more than 2 years from
disseminated localized scleroderma (LS)(Figure 1) markedly improved during treatment with …

The treatment of systemic sclerosis (scleroderma) is difficult and remains a great challenge
to the clinician. Because the cause is unknown, therapies are directed to improve peripheral …

Objective The natural history of changes in skin thickening in diffuse scleroderma is quite
variable, but the significance of these changes is not clear. Clinical trials are using changes …

Opinion statement Cutaneous fibrosing disorders encompass a diverse array of diseases
united by the presence of varying degrees of dermal sclerosis. The quality and distribution of …

RESULTS ALA-PDT was well tolerated, there was only a slight stinging by the end of
irradiation. In all patients sclerosis regressed greatly, skin score markedly decreased and …