The chronic inflammatory bowel disease ulcerative colitis (UC) occurs commonly in the US
and other Western countries, but its etiology is unknown. An association between UC and an …

Ulcerative colitis (UC) is characterized by repeated flare-ups of inflammation that can lead to
oncogenic insults to the colonic epithelial. UC-associated carcinogenesis presents a …

Oxidative stress is defined as an imbalance between generation of reactive oxygen species
(ROS) and decreased antioxidant defense systems. Oxidative stress develops particularly in …

Patients with ulcerative colitis and Crohn's disease are at increased risk for developing
colorectal cancer (CRC). Chronic inflammation is believed to promote carcinogenesis. The …

One of the most serious complications of ulcerative colitis is the development of colorectal
cancer. Screening patients with ulcerative colitis by standard histological examination of …

One of the contributory causes of colon cancer is the negative effect of reactive oxygen
species on DNA repair mechanisms. Currently, there is a growing support for the concept …

Colorectal neoplasia in ulcerative colitis—recent advances It is recognized that ulcerative
colitis (UC) predisposes to the development of colorectal adenocarcinoma (CRC), and the …

The colon and small intestine have inherent differences (eg redox status) that may explain
the variation in cancer occurrence at these two sites. This study examined basal and …

Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer mortality worldwide. Colitis-associated colorectal cancer (CAC) is a subtype …

Ulcerative colitis is an idiopathic, chronic and relapsing inflammatory bowel disease, which
elicits the risk of colorectal cancer, the third most common malignancy in humans. It has …