[PDF][PDF] Disordered gut microbiota and alterations in metabolic patterns are associated with atrial fibrillation

K Zuo, J Li, K Li, C Hu, Y Gao, M Chen, R Hu… - …, 2019 - academic.oup.com
Background With the establishment of the heart-gut axis concept, accumulating studies
suggest that the gut microbiome plays an important role in the pathogenesis of …

Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications

M Gawałko, TA Agbaedeng, A Saljic… - Cardiovascular …, 2022 - academic.oup.com
Recent preclinical and observational cohort studies have implicated imbalances in gut
microbiota composition as a contributor to atrial fibrillation (AF). The gut microbiota is a …

The correlation between gut microbiome and atrial fibrillation: pathophysiology and therapeutic perspectives

N Li, L Wang, L Li, MZ Yang, QX Wang, XW Bai… - Military Medical …, 2023 - Springer
Regulation of gut microbiota and its impact on human health is the theme of intensive
research. The incidence and prevalence of atrial fibrillation (AF) are continuously escalating …

Gut microbial composition in patients with atrial fibrillation: effects of diet and drugs

T Tabata, T Yamashita, K Hosomi, J Park, T Hayashi… - Heart and vessels, 2021 - Springer
Atrial fibrillation (AF) reduces the quality of life by triggering stroke and heart failure. The
association between AF onset and gut metabolites suggests a causal relationship between …

Gut microbiome and atrial fibrillation—results from a large population-based study

J Palmu, CS Börschel, A Ortega-Alonso, L Markó… - …, 2023 - thelancet.com
Background Atrial fibrillation (AF) is an important heart rhythm disorder in aging populations.
The gut microbiome composition has been previously related to cardiovascular disease risk …

Gut microbiota dysbiosis induced by a high-fat diet increases susceptibility to atrial fibrillation

B Kong, H Fu, Z Xiao, Y Zhou, W Shuai… - Canadian Journal of …, 2022 - Elsevier
Background Obesity is a significant risk factor for atrial fibrillation (AF), and the gut
microbiota is closely related to obesity-induced diseases. However, whether the gut …

Gut microbiota dysbiosis promotes age-related atrial fibrillation by lipopolysaccharide and glucose-induced activation of NLRP3-inflammasome

Y Zhang, S Zhang, B Li, Y Luo, Y Gong… - Cardiovascular …, 2022 - academic.oup.com
Aims Ageing is the most significant contributor to the increasing prevalence of atrial
fibrillation (AF). The gut microbiota dysbiosis is involved in age-related diseases. However …

[HTML][HTML] Commensal microbe-derived SCFA alleviates atrial fibrillation via GPR43/NLRP3 signaling

K Zuo, C Fang, Z Liu, Y Fu, Y Liu, L Liu… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Rationale: Dysbiotic gut microbiota (GM) and NLRP3 inflammasome are proarrhythmic
factors in atrial fibrillation (AF). Herein, whether short-chain fatty acid (SCFA) produced from …

Gut microbiome and its role in cardiovascular diseases

S Ahmadmehrabi, WHW Tang - Current opinion in cardiology, 2017 - journals.lww.com
Although our understanding of gut microbiota–host interactions has increased recently;
many questions remain about the mechanistic links between the gut microbiome and CVD …

Heart failure is associated with depletion of core intestinal microbiota

M Luedde, T Winkler, FA Heinsen… - ESC Heart …, 2017 - Wiley Online Library
Aims In spite of current medical treatment approaches, mortality of chronic heart failure (HF)
remains high and novel treatment modalities are thus urgently needed. A recent theory …