The obesity paradox–a reality that requires explanation and clinical interpretation

JB Dixon, GW Lambert - Atherosclerosis, 2013 - atherosclerosis-journal.com
Obesity is a chronic relapsing disease that is clearly associated with increased risk of
developing type 2 diabetes, cardiovascular disease, and many cancers leading to reduced …

Obesity paradox and mortality in adults with and without incident type 2 diabetes: a matched population-level cohort study

E Badrick, M Sperrin, IE Buchan… - BMJ Open Diabetes …, 2017 - drc.bmj.com
Objective Among adults with type 2 diabetes (T2D), several (but not all) studies show that
being overweight (body mass index (BMI): 25.0–29.9 kg/m2) or obese I (BMI: 30.0–34.9 …

The obesity paradox in type 2 diabetes and mortality

DK Tobias, JAE Manson - American Journal of Lifestyle …, 2018 - journals.sagepub.com
The obesity paradox for survival among individuals with type 2 diabetes has been observed
in some but not all studies. Conflicting evidence for the role of overweight and obesity in all …

Declining cardiovascular mortality and increasing obesity: a paradox

A Rosengren - Cmaj, 2009 - Can Med Assoc
How can the increased rates of obesity be reconciled with the rapid decrease in mortality
related to coronary artery disease observed over the last decades in most Western …

Association of body mass index with mortality in cardiovascular disease: new insights into the obesity paradox from multiple perspectives

JY Xia, DM Lloyd-Jones, SS Khan - Trends in cardiovascular medicine, 2019 - Elsevier
Over the past 4 decades, prevalence of obesity has increased rapidly at both the national
and global level and presents a major public health challenge. Obesity is associated with …

Overweight and increased cardiovascular mortality: no French paradox

FB Hu - Hypertension, 2005 - Am Heart Assoc
Obesity has reached epidemic proportions in the United States. Currently, one third of US
adults are classified as obese and another one third as overweight. Obesity is also a …

[PDF][PDF] The evidence for an obesity paradox in type 2 diabetes mellitus

SJ Han, EJ Boyko - Diabetes & Metabolism Journal, 2018 - synapse.koreamed.org
Although overweight/obesity is a major risk factor for the development of type 2 diabetes
mellitus, there is increasing evidence that overweight or obese patients with type 2 diabetes …

Obesity and cardiovascular outcomes: a review

K Ghoorah, P Campbell, A Kent… - European Heart …, 2016 - journals.sagepub.com
The prevalence of obesity is increasing at an epidemic rate globally with more than 1 billion
adults overweight and at least 300 million of them clinically obese. This is expected to rise …

The obesity paradox: perception vs knowledge

PA Ades, PD Savage - Mayo Clinic Proceedings, 2010 - mayoclinicproceedings.org
Data from several epidemiological studies, including the Framingham Heart Study, have
found a positive relationship between obesity and mortality, in particular cardiovascular …

Body-mass index and mortality among adults with incident type 2 diabetes

DK Tobias, A Pan, CL Jackson… - … England Journal of …, 2014 - Mass Medical Soc
Background The relation between body weight and mortality among persons with type 2
diabetes remains unresolved, with some studies suggesting decreased mortality among …