We studied eleven patients during 14 attempts at weaning from mechanical ventilation to
determine whether central ventilatory drive, measured as airway occlusion pressure 0.1 s …

Airway occlusion pressure (PO. 1) and the ratio of breathing frequency (f) to tidal volume
(VT)(fNt) are good predictors of weaning outcome. However, the specificity of fNT in …

This article reviews the factors that determine a patient's ability to resume spontaneous
breathing following a period of mechanical ventilation, the use of physiologic measurements …

We prospectively examined the pattern of breathing in patients being weaned from
mechanical ventilation: one group (n= 10) underwent a successful weaning trial and were …

Objective: To assess the diagnostic accuracy of several measured and calculated indexes
for early prediction of weaning outcome, and to study the value of supplemental inspiratory …

We identified 65 observational studies of weaning predictors that had been reported in 70
publications. After grouping predictors with similar names but different thresholds, the …

Several variables are recommended for identifying if a patient is ready for a trial of weaning
from mechanical ventilation, but there is no agreement as to whether monitoring any …

We have previously shown (Am. J. Respir. Crit. Care Med. 1995; 152: 1248–1255) that in
patients needing mechanical ventilation, the load imposed on the inspiratory muscles is …

Weaning from mechanical ventilation remains a major challenge for critical care physicians.
Because subjective criteria are inaccurate, objective measurements consisting of clinical …

Weaning from mechanical ventilation is a period of transition from total ventilatory support to
spontaneous breathing. It represents a relevant clinical problem because as many as 25 …