Fluorescent metallacycle-cored polymers via covalent linkage and their use as contrast agents for cell imaging
The covalent linkage of supramolecular monomers provides a powerful strategy for
constructing dynamic polymeric materials whose properties can be readily tuned either by …
constructing dynamic polymeric materials whose properties can be readily tuned either by …
Metallacycle-cored supramolecular polymers: fluorescence tuning by variation of substituents
Herein, we present a method for the preparation of supramolecular polymers with tunable
fluorescence via the combination of metal–ligand coordination and phenanthrene-21-crown …
fluorescence via the combination of metal–ligand coordination and phenanthrene-21-crown …
Tetraphenylethene-based highly emissive metallacage as a component of theranostic supramolecular nanoparticles
A theranostic agent combines diagnostic reporter with therapeutic activity in a single entity,
an approach that seeks to increase the efficacy of cancer treatment. Herein, we describe the …
an approach that seeks to increase the efficacy of cancer treatment. Herein, we describe the …
Biomedical applications of Pt (II) metallacycle/metallacage-based agents: From mono-chemotherapy to versatile imaging contrasts and theranostic platforms
Platinum-based coordination chemistry has laid the foundation for the development of
numerous metal complexes and provoked their applications in cancer chemotherapy. It is …
numerous metal complexes and provoked their applications in cancer chemotherapy. It is …
Glycosylated BODIPY-incorporated Pt (II) metallacycles for targeted and synergistic chemo-photodynamic therapy
G Durán-Sampedro, EY Xue… - Journal of Medicinal …, 2023 - ACS Publications
Pt (II)-BODIPY complexes combine the chemotherapeutic activity of Pt (II) with the
photocytotoxicity of BODIPYs. Additional conjugation with targeting ligands can boost the …
photocytotoxicity of BODIPYs. Additional conjugation with targeting ligands can boost the …
Antitumor activity of a unique polymer that incorporates a fluorescent self-assembled metallacycle
Despite the well-known anticancer activity of mono-and multinuclear platinum complexes,
studies of the antitumor performances of platinum-based supramolecular coordination …
studies of the antitumor performances of platinum-based supramolecular coordination …
Recent advances in luminescent metallacycles/metallacages for biomedical imaging and cancer therapy
Y Pang, C Li, H Deng, Y Sun - Dalton Transactions, 2022 - pubs.rsc.org
Small molecule metal-based drugs have shown great achievements in preclinical and
clinical applications. In particular, platinum based antitumor drugs are well established in …
clinical applications. In particular, platinum based antitumor drugs are well established in …
Recent developments in the construction of metallacycle/metallacage-cored supramolecular polymers via hierarchical self-assembly
B Li, T He, Y Fan, X Yuan, H Qiu, S Yin - Chemical Communications, 2019 - pubs.rsc.org
Supramolecular polymers have received considerable attention during the last few decades
due to their scientific value in polymer chemistry and profound implications for future …
due to their scientific value in polymer chemistry and profound implications for future …
Metallacycle-cored supramolecular assemblies with tunable fluorescence including white-light emission
Control over the fluorescence of supramolecular assemblies is crucial for the development
of chemosensors and light-emitting materials. Consequently, the postsynthetic modification …
of chemosensors and light-emitting materials. Consequently, the postsynthetic modification …
Self-assembled Pt (II) metallacycles enable precise cancer combination chemotherapy
P Zhang, Z Zhou, W Long, Y Yan, Y Li… - Proceedings of the …, 2022 - National Acad Sciences
Combination chemotherapy, which involves the simultaneous use of multiple anticancer
drugs in adequate combinations to disrupt multiple mechanisms associated with tumor …
drugs in adequate combinations to disrupt multiple mechanisms associated with tumor …