Abscisic acid stimulates glucagon-like peptide-1 secretion from L-cells and its oral administration increases plasma glucagon-like peptide-1 levels in rats

S Bruzzone, M Magnone, E Mannino, G Sociali… - PLoS …, 2015 - journals.plos.org
In recent years, Abscisic Acid (ABA) has been demonstrated to be involved in the regulation
of glucose homeostasis in mammals as an endogenous hormone, by stimulating both …

Abscisic acid stimulates the release of insulin and of GLP‐1 in the rat perfused pancreas and intestine

V Booz, CB Christiansen, RE Kuhre… - Diabetes/Metabolism …, 2019 - Wiley Online Library
Aims Previous results indicate that nanomolar concentrations of abscisic acid (ABA)
stimulate insulin release from β‐pancreatic cells in vitro and that oral ABA at 50 mg/kg …

Abscisic acid: a novel nutraceutical for glycemic control

E Zocchi, R Hontecillas, A Leber, A Einerhand… - Frontiers in …, 2017 - frontiersin.org
Abscisic acid is naturally present in fruits and vegetables, and it plays an important role in
managing glucose homeostasis in humans. According to the latest US dietary survey, about …

The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts

S Bruzzone, P Ameri, L Briatore, E Mannino… - The FASEB …, 2012 - Wiley Online Library
The plant hormone abscisic acid (ABA) is released from glucose‐challenged human
pancreatic β cells and stimulates insulin secretion. We investigated whether plasma ABA …

Abscisic acid improves insulin action on glycemia in insulin-deficient mouse models of type 1 diabetes

M Magnone, S Spinelli, G Begani, L Guida, L Sturla… - Metabolites, 2022 - mdpi.com
Abscisic acid (ABA), a plant hormone, has recently been shown to play a role in glycemia
regulation in mammals, by stimulating insulin-independent glucose uptake and metabolism …

Impaired increase of plasma abscisic acid in response to oral glucose load in type 2 diabetes and in gestational diabetes

P Ameri, S Bruzzone, E Mannino, G Sociali… - PLoS …, 2015 - journals.plos.org
The plant hormone abscisic acid (ABA) is present and active in humans, regulating glucose
homeostasis. In normal glucose tolerant (NGT) human subjects, plasma ABA (ABAp) …

Insulin-independent stimulation of skeletal muscle glucose uptake by low-dose abscisic acid via AMPK activation

M Magnone, L Emionite, L Guida, T Vigliarolo… - Scientific reports, 2020 - nature.com
Abscisic acid (ABA) is a plant hormone active also in mammals where it regulates, at
nanomolar concentrations, blood glucose homeostasis. Here we investigated the …

Abscisic acid: a new mammalian hormone regulating glucose homeostasis

S Bruzzone, P Ameri, L Sturla, L Guida, A De Flora… - …, 2012 - ingentaconnect.com
Abscisic acid (ABA) is a hormone conserved in plants and animals with the common role of
regulating the response to biotic and abiotic environmental stimuli. Plants and animals share …

Abscisic acid: A conserved hormone in plants and humans and a promising aid to combat prediabetes and the metabolic syndrome

M Magnone, L Sturla, L Guida, S Spinelli, G Begani… - Nutrients, 2020 - mdpi.com
Abscisic acid (ABA) is a hormone with a very long evolutionary history, dating back to the
earliest living organisms, of which modern (ABA-producing) cyanobacteria are likely the …

Abscisic acid is an endogenous stimulator of insulin release from human pancreatic islets with cyclic ADP ribose as second messenger

S Bruzzone, N Bodrato, C Usai, L Guida… - Journal of Biological …, 2008 - ASBMB
Abscisic acid (ABA) is a plant stress hormone recently identified as an endogenous pro-
inflammatory cytokine in human granulocytes. Because paracrine signaling between …