The role of the respiratory microbiome in asthma

CD Campbell, M Gleeson, I Sulaiman - Frontiers in Allergy, 2023 - frontiersin.org
Asthma is a common airways disease and the human microbiome plays an increasingly
recognised role in asthma pathogenesis. Furthermore, the respiratory microbiome varies …

The gut microbiome and ozone-induced airway hyperresponsiveness. Mechanisms and therapeutic prospects

H Tashiro, SA Shore - American journal of respiratory cell and …, 2021 - atsjournals.org
In recent years, several new asthma therapeutics have been developed. Although many of
these agents show promise in treating allergic asthma, they are less effective against …

Microbiota, regulatory T cell subsets, and allergic disorders

C Ohnmacht - Allergo journal international, 2016 - Springer
Epidemiologic studies revealed a crucial role of the environment for the increased
prevalence of allergic disorders. The microbiota as part of our immediate environment …

Mycobacterium-induced Th1, helminths-induced Th2 cells and the potential vaccine candidates for allergic asthma: Imitation of natural infection

MH Abdelaziz, X Ji, J Wan, FA Abouelnazar… - Frontiers in …, 2021 - frontiersin.org
Bronchial asthma is one of the most chronic pulmonary diseases and major public health
problems. In general, asthma prevails in developed countries than developing countries …

The role of lower airway dysbiosis in asthma: dysbiosis and asthma

J Lu, L Xiong, X Zhang, Z Liu, S Wang… - Mediators of …, 2017 - Wiley Online Library
With the development of culture‐independent techniques, numerous studies have
demonstrated that the lower airway is not sterile in health and harbors diverse microbial …

Future prospect of oral microbiota influencing allergy/asthma development

Y Cai, Y Zhao, Y Kang, Y Yang - Frontiers in Microbiology, 2022 - frontiersin.org
Allergic diseases have become a primary public health issue in a moderately prosperous
society. Colonization of microorganisms early in life appears to be significant in guiding the …

Human matters in asthma: Considering the microbiome in pulmonary health

SJ Marathe, MA Snider, AS Flores-Torres… - Frontiers in …, 2022 - frontiersin.org
Microbial communities form an important symbiotic ecosystem within humans and have
direct effects on health and well-being. Numerous exogenous factors including airborne …

Reduced airway microbiota diversity is associated with elevated allergic respiratory inflammation

W Yu, X Yuan, X Xu, R Ding, L Pang, Y Liu… - Annals of Allergy …, 2015 - Elsevier
Background An increased prevalence of allergic disorders in developed countries has been
associated with decreased exposure to environmental micro-organisms and an alteration of …

Role of the microbiome in allergic disease development

AC Aguilera, IA Dagher, KM Kloepfer - Current allergy and asthma reports, 2020 - Springer
Abstract Purpose of Review Evidence suggests that the microbiome of the skin,
gastrointestinal tract, and airway contribute to health and disease. As we learn more about …

Interactions between microbiome and underlying mechanisms in asthma

P Losol, M Sokolowska, YS Chang - Respiratory Medicine, 2023 - Elsevier
Microbiome primes host innate immunity in utero and play fundamental roles in the
development, training, and function of the immune system throughout the life. Interplay …