In this work, the B→ Z transition of poly (dG-dC)· poly (dG-dC) and the B→ A transition of
poly (dG)· poly (dC) and of calf thymus (CT) DNA fragments modified by antitumor …

The trifunctional dinuclear platinum compounds 1, 2/c, c [{cis-PtCl (NH3) 2} μ-H2N (CH2)
6NH2 {cis-PtCl2 (NH3)}]+ and 1, 2/t, c [{trans-PtCl (NH3) 2} μ-H2N (CH2) 6NH2 {cis-PtCl2 …

Polynuclear platinum compounds demonstrate many novel phenomena in their interactions
with DNA and proteins as well as novel anti-cancer activities. Previous studies indicated that …

Dinuclear bis (platinum) complexes have been shown previously to induce the B→ Z
transition in synthetic DNAs (Nucleic Acids Res. 7, 1697–1703; J. Inorganic Biochem. 54 …

Modifications of natural DNA in a cell‐free medium by dinuclear bisplatinum complexes with
equivalent coordination spheres, represented by the general formula [{trans‐PtCl (NH3) 2} 2 …

The novel phase II anticancer drug BBR3464 ([{trans-PtCl (NH 3) 2} 2-µ-{trans-Pt (NH 3) 2
(NH 2 (CH 2) 6 NH 2) 2}](NO 3) 4) forms a 1, 4-interstrand cross-link adduct with the self …

The synthesis of the formally monofunctional bis (platinum) complex [{Pt (NH} 3) 3 μ-H 2 N
(CH 2) 4 NH 2-{trans-PtCl (NH 3) 2}] 3+(1, 0/t) is reported. The interactions of this species …

In this work, the reversibility of both the B→ Z and B→ A conformational change in polymer
DNA induced by polynuclear platinum compounds was studied. The compounds examined …

The novel anticancer drug ([{trans-PtCl (NH3) 2} 2-μ-{trans-Pt (NH3) 2 (NH2 (CH2) 6NH2)
2}](NO3) 4)(BBR3464, 1, 0, 1/t, t, t, TPC) forms a 1, 4-interstrand cross-linked adduct with the …

The DNA binding and interstrand cross-linking properties of the dinuclear platinum complex
[{cis-Pt (NH3) 2Cl} 2bpsu](NO3) 2 (bpsu is 4, 4′-dipyridyl sulfide)(II) and the mononuclear …