A comparison of methylprednisolone and dexamethasone in intensive care patients with COVID-19

JJ Ko, C Wu, N Mehta, N Wald-Dickler… - Journal of intensive …, 2021 - journals.sagepub.com
Objectives: This study retrospectively compares the effectiveness of methylprednisolone to
dexamethasone in patients with severe acute respiratory syndrome coronavirus 2 (SARS …

Clinical outcomes associated with methylprednisolone in mechanically ventilated patients with COVID-19

BC Nelson, J Laracy, S Shoucri, D Dietz… - Clinical Infectious …, 2021 - academic.oup.com
Background The efficacy and safety of methylprednisolone in mechanically ventilated
patients with acute respiratory distress syndrome resulting from coronavirus disease 2019 …

High‐dose methylprednisolone in nonintubated patients with severe COVID‐19 pneumonia

A Papamanoli, J Yoo, P Grewal… - European journal of …, 2021 - Wiley Online Library
Background Recent trials with dexamethasone and hydrocortisone have demonstrated
benefit in patients with coronavirus disease 2019 (COVID‐19). Data on methylprednisolone …

Prolonged higher dose methylprednisolone versus conventional dexamethasone in COVID-19 pneumonia: a randomised controlled trial (MEDEAS)

F Salton, P Confalonieri, S Centanni… - European …, 2023 - Eur Respiratory Soc
Background Dysregulated systemic inflammation is the primary driver of mortality in severe
coronavirus disease 2019 (COVID-19) pneumonia. Current guidelines favour a 7–10-day …

Corticosteroid therapy in critically ill patients with COVID-19: a multicenter, retrospective study

Y Li, Q Meng, X Rao, B Wang, X Zhang, F Dong, T Yu… - Critical Care, 2020 - Springer
Background Corticoid therapy has been recommended in the treatment of critically ill
patients with COVID-19, yet its efficacy is currently still under evaluation. We investigated the …

Dexamethasone in hospitalized patients with Covid-19

RECOVERY Collaborative Group - New England Journal of …, 2021 - Mass Medical Soc
Abstract Background Coronavirus disease 2019 (Covid-19) is associated with diffuse lung
damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby …

[HTML][HTML] Dexamethasone as risk-factor for ICU-acquired respiratory tract infections in severe COVID-19

LF Reyes, A Rodriguez, A Bastidas, D Parra-Tanoux… - Journal of critical …, 2022 - Elsevier
Purpose Dexamethasone is the only drug that has consistently reduced mortality in patients
with COVID-19, especially in patients needing oxygen or invasive mechanical ventilation …

Dexamethasone in hospitalized patients with Covid-19-preliminary report

L Chappell, P Horby, WS Lim… - The New England …, 2020 - kclpure.kcl.ac.uk
Background: Coronavirus disease 2019 (Covid-19) is associated with diffuse lung damage.
Glucocorticoids may modulate inflammation-mediated lung injury and thereby reduce …

[PDF][PDF] Short-term dexamethasone in Sars-CoV-2 patients

V Selvaraj, K Dapaah-Afriyie, A Finn, TP Flanigan - RI Med J, 2020 - rimed.org
ABSTRACT BACKGROUND: Dexamethasone, a synthetic glucocorticoid, has anti-
inflammatory and immunosuppressive properties. There is a hyperinflammatory response …

Early use of corticosteroid may prolong SARS-CoV-2 shedding in non-intensive care unit patients with COVID-19 pneumonia: a multicenter, single-blind, randomized …

X Tang, YM Feng, JX Ni, JY Zhang, LM Liu, K Hu… - Respiration, 2021 - karger.com
Background: There is still no clinical evidence available to support or to oppose
corticosteroid treatment for coronavirus disease 2019 (COVID-19) pneumonia. Objective: To …