Brain-Derived Neurotrophic Factor (BDNF) Preserves the Functional Integrity of Neural Networks in the β-Amyloidopathy Model in vitro
EV Mitroshina, RS Yarkov, TA Mishchenko… - Frontiers in Cell and …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a widespread chronic neurodegenerative pathology
characterized by synaptic dysfunction, partial neuronal death, cognitive decline and memory …
characterized by synaptic dysfunction, partial neuronal death, cognitive decline and memory …
Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease
Downregulation of brain-derived neurotrophic factor (BDNF) in the cortex occurs early in the
progression of Alzheimer's disease (AD). Since BDNF plays a critical role in neuronal …
progression of Alzheimer's disease (AD). Since BDNF plays a critical role in neuronal …
Transduced PTD-BDNF fusion protein protects against beta amyloid peptide-induced learning and memory deficits in mice
JP Zhou, ZG Feng, BL Yuan, SZ Yu, Q Li, HY Qu… - Brain research, 2008 - Elsevier
Brain-derived neurotrophic factor (BDNF) promotes the survival and differentiation of
hippocampal, cortical, and basal forebrain cholinergic neurons. However, the efficacy of …
hippocampal, cortical, and basal forebrain cholinergic neurons. However, the efficacy of …
Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in …
DJ Garzon, M Fahnestock - Journal of Neuroscience, 2007 - Soc Neuroscience
Alzheimer's disease (AD) is a senile dementia characterized by amyloid plaques,
neurofibrillary tangles, and synaptic and cell loss. The “amyloid cascade” hypothesis …
neurofibrillary tangles, and synaptic and cell loss. The “amyloid cascade” hypothesis …
Induction of brain-derived neurotrophic factor in plaque-associated glial cells of aged APP23 transgenic mice
GJ Burbach, R Hellweg, CA Haas… - Journal of …, 2004 - Soc Neuroscience
Brain-derived neurotrophic factor (BDNF) is a versatile neurotrophic factor that has been
implicated in cell survival, cell differentiation, axonal growth, and activity-dependent synaptic …
implicated in cell survival, cell differentiation, axonal growth, and activity-dependent synaptic …
Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's disease
SS Jiao, LL Shen, C Zhu, XL Bu, YH Liu, CH Liu… - Translational …, 2016 - nature.com
Reduced expression of brain-derived neurotrophic factor (BDNF) has a crucial role in the
pathogenesis of Alzheimer's disease (AD), which is characterized with the formation of …
pathogenesis of Alzheimer's disease (AD), which is characterized with the formation of …
Brain-derived neurotrophic factor ameliorates learning deficits in a rat model of Alzheimer's disease induced by aβ1-42
An emerging body of data suggests that the early onset of Alzheimer's disease (AD) is
associated with decreased brain-derived neurotrophic factor (BDNF). Because BDNF plays …
associated with decreased brain-derived neurotrophic factor (BDNF). Because BDNF plays …
Impact of an additional chronic BDNF reduction on learning performance in an Alzheimer mouse model
L Psotta, C Rockahr, M Gruss, E Kirches… - Frontiers in behavioral …, 2015 - frontiersin.org
There is increasing evidence that brain-derived neurotrophic factor (BDNF) plays a crucial
role in Alzheimer's disease (AD) pathology. A number of studies demonstrated that AD …
role in Alzheimer's disease (AD) pathology. A number of studies demonstrated that AD …
Hippocampal BDNF expression in a tau transgenic mouse model
S Burnouf, K Belarbi, L Troquier… - Current Alzheimer …, 2012 - ingentaconnect.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by extracellular
accumulation of amyloid deposits and intracellular neurofibrillary tangles (NFT) composed of …
accumulation of amyloid deposits and intracellular neurofibrillary tangles (NFT) composed of …
Brain-derived neurotrophic factor in Alzheimer's disease: risk, mechanisms, and therapy
JH Song, JT Yu, L Tan - Molecular neurobiology, 2015 - Springer
Brain-derived neurotrophic factor (BDNF) has a neurotrophic support on neuron of central
nervous system (CNS) and is a key molecule in the maintenance of synaptic plasticity and …
nervous system (CNS) and is a key molecule in the maintenance of synaptic plasticity and …