Is the development of Modic changes associated with clinical symptoms? A 14-month cohort study with MRI
RK Jensen, C Leboeuf-Yde, N Wedderkopp… - European Spine …, 2012 - Springer
Abstract Purpose Modic changes (MCs) have been suggested to be a diagnostic subgroup
of low back pain (LBP). However, the clinical implications of MCs remain unclear. For this …
of low back pain (LBP). However, the clinical implications of MCs remain unclear. For this …
The association of modic changes and chronic low back pain: a systematic review
Background Modic changes (MC) have been proposed as a cause of low back pain (LBP).
However, the proposition remains controversial. There is uncertainty over the existence or …
However, the proposition remains controversial. There is uncertainty over the existence or …
Modic changes and associated features in Southern European chronic low back pain patients
Background context Conflicting reports exist regarding the prevalence of Modic changes
among low back pain (LBP) patients and factors associated with their existence. Purpose To …
among low back pain (LBP) patients and factors associated with their existence. Purpose To …
Association between types of Modic changes in the lumbar region and low back pain in a large cohort: the Wakayama spine study
Y Mera, M Teraguchi, H Hashizume, H Oka… - European Spine …, 2021 - Springer
Purpose The clinical significance of Modic changes in low back pain (LBP) is yet to be
clarified. Thus, this study aimed to examine the association between Modic changes and …
clarified. Thus, this study aimed to examine the association between Modic changes and …
Are Modic changes in patients with chronic low back pain indicative of a worse clinical course? 10 years of follow-up
LM Romero-Muñoz, A Barriga-Martín… - Revista Española de …, 2018 - Elsevier
Objective Establish the long-term (10 years) predictive value of Modic changes in the course
of lumbar pain and the need for surgical treatment. Material and method Observational …
of lumbar pain and the need for surgical treatment. Material and method Observational …
Chronic low back pain in relation to Modic changes, bony endplate lesions, and disc degeneration in a prospective MRI study
K Luoma, T Vehmas, L Kerttula, M Grönblad… - European Spine …, 2016 - Springer
Purpose To clarify the significance of Modic changes, bony endplate lesions, and disc
degeneration as predictors of chronic low back pain (LBP) during 1-year follow-up. Methods …
degeneration as predictors of chronic low back pain (LBP) during 1-year follow-up. Methods …
Modic changes-An evidence-based, narrative review on its patho-physiology, clinical significance and role in chronic low back pain
VK Viswanathan, AP Shetty, S Rajasekaran - Journal of clinical …, 2020 - Elsevier
Objective Lumbar degenerative spinal ailments are the most important causes for chronic
low back pain. Modic changes (MC) are vertebral bone marrow signal intensity changes …
low back pain. Modic changes (MC) are vertebral bone marrow signal intensity changes …
Serum biomarkers for Modic changes in patients with chronic low back pain
J Karppinen, K Koivisto, J Ketola, M Haapea… - European Spine …, 2021 - Springer
Abstract Purpose Lumbar Modic change (MC) can serve as a diagnostic marker as well as
an independent source of chronic low back pain (CLBP). This study aimed to test for the …
an independent source of chronic low back pain (CLBP). This study aimed to test for the …
Inflammatory pain pattern and pain with lumbar extension associated with Modic 1 changes on MRI: a prospective case–control study of 120 patients
Purpose To compare, in a case–control study, clinical characteristics of patients with low
back pain (LBP) with and without Modic 1 signal changes on MRI. Methods Patients with …
back pain (LBP) with and without Modic 1 signal changes on MRI. Methods Patients with …
The association between Modic changes and pain during 1-year follow-up in patients with lumbar radicular pain
EI Schistad, A Espeland, LJ Rygh, C Røe, J Gjerstad - Skeletal radiology, 2014 - Springer
Abstract Objective To examine whether Modic changes influence pain during a 1-year follow-
up in patients with lumbar radicular pain. Materials and Methods A total of 243 patients with …
up in patients with lumbar radicular pain. Materials and Methods A total of 243 patients with …