The impact of probiotic supplementation on cognitive, pathological and metabolic markers in a transgenic mouse model of Alzheimer's disease

TS Webberley, G Masetti, RJ Bevan… - Frontiers in …, 2022 - frontiersin.org
Brain degenerative disorders such as Alzheimer's disease (AD) can be exacerbated by
aberrant metabolism. Supplementation with probiotic bacteria is emerging as a promising …

Therapeutic effects of probiotics on neurotoxicity induced by clindamycin and propionic acid in juvenile hamsters

N Al-Orf, A El-Ansary, G Bjørklund, N Moubayed… - Metabolic Brain …, 2018 - Springer
The present study investigated the therapeutic effects of probiotics on brain intoxication
induced by clindamycin and propionic acid (PPA) in hamsters. Fifty golden Syrian hamsters …

[HTML][HTML] Proneurogenic and neuroprotective effect of a multi strain probiotic mixture in a mouse model of acute inflammation: Involvement of the gut-brain axis

C Petrella, G Strimpakos, A Torcinaro, S Middei… - Pharmacological …, 2021 - Elsevier
Neuroinflammation can severely affect brain homeostasis and adult hippocampal
neurogenesis with detrimental effects on cognitive processes. Brain and gut are intimately …

Animal models used for studying the benefits of probiotics in Neurodegeneration

G Divyashri, SG Prapulla - Probiotic Research in Therapeutics: Volume 4 …, 2022 - Springer
Abstract Neurodegenerative sicknesses, viz., Alzheimer's disease, Parkinson's disease,
Huntington's disease, amyotrophic lateral sclerosis, frontotemporal dementia, and the …

Neuroprotective and immunomodulatory effects of probiotics in a rat model of Parkinson's disease

I Parra, I Martínez, L Vásquez-Celaya… - Neurotoxicity …, 2023 - Springer
It is now well recognized that a bidirectional relationship between gut microbiota and the
brain, referred to as the gut-brain axis, plays a prominent role in maintaining homeostasis …

Preventive Effect of Saccharomyces boulardii on Memory Impairment Induced by Lipopolysaccharide in Rats

F Babaei, M Mirzababaei, L Dargahi… - ACS chemical …, 2022 - ACS Publications
Recent studies have indicated that dysfunction of gut microbiota, living microorganisms of
the digestive tract, plays a role in the pathogenesis of neurodegenerative disorders …

A novel Mediterranean diet-inspired supplement ameliorates cognitive, microbial, and metabolic deficits in a mouse model of low-grade inflammation

MG Pontifex, E Connell, G Le Gall, L Lang… - Gut …, 2024 - Taylor & Francis
The Mediterranean diet (MD) and its bioactive constituents have been advocated for their
neuroprotective properties along with their capacity to affect gut microbiota speciation and …

SLAB51 probiotic formulation activates SIRT1 pathway promoting antioxidant and neuroprotective effects in an AD mouse model

L Bonfili, V Cecarini, M Cuccioloni, M Angeletti… - Molecular …, 2018 - Springer
The gut-brain axis is a bidirectional communication network functionally linking the gut and
the central nervous system (CNS). Based on this, the rational manipulation of intestinal …

Probiotic Lacticaseibacillus rhamnosus HA-114 suppresses age-dependent neurodegeneration via mitochondrial beta-oxidation

A Labarre, E Guitard, G Tossing, E Bareke… - 2020 - researchsquare.com
The human microbiota is believed to influence health. Microbiome dysbiosis may be linked
to neurological conditions like Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) …

Neurodegenerative microbially-shaped diseases: oxidative stress meets neuroinflammation

DF Silva, N Empadinhas, SM Cardoso, AR Esteves - Antioxidants, 2022 - mdpi.com
Inflammation and oxidative stress characterize a number of chronic conditions including
neurodegenerative diseases and aging. Inflammation is a key component of the innate …