The safety of ustekinumab treatment in patients with moderate‐to‐severe psoriasis and latent tuberculosis infection
TF Tsai, V Ho, M Song, P Szapary, T Kato… - British Journal of …, 2012 - academic.oup.com
Background Ustekinumab is a monoclonal antibody that targets interleukin (IL)‐12/23 p40 to
treat psoriasis. The IL‐12 pathway is also important in regulating immunity to Mycobacterium …
treat psoriasis. The IL‐12 pathway is also important in regulating immunity to Mycobacterium …
The safety profile of ustekinumab in the treatment of patients with psoriasis and concurrent hepatitis B or C
HY Chiu, CH Chen, MS Wu, YP Cheng… - British Journal of …, 2013 - academic.oup.com
Background Ustekinumab, an interleukin (IL)‐12 and IL‐23 blocker, has emerged as a new
therapeutic option for patients with psoriasis. It is generally well tolerated but safety data on …
therapeutic option for patients with psoriasis. It is generally well tolerated but safety data on …
Long-term safety experience of ustekinumab in patients with moderate to severe psoriasis (Part II of II): results from analyses of infections and malignancy from pooled …
KB Gordon, KA Papp, RG Langley, V Ho… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Ustekinumab targets interleukin (IL)-12 and IL-23 in the treatment of
moderate to severe psoriasis. OBJECTIVE: We sought to evaluate the impact of …
moderate to severe psoriasis. OBJECTIVE: We sought to evaluate the impact of …
Long-term safety experience of ustekinumab in patients with moderate-to-severe psoriasis (Part I of II): results from analyses of general safety parameters from pooled …
M Lebwohl, C Leonardi, CEM Griffiths, JC Prinz… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Ustekinumab targets interleukin (IL)-12 and IL-23 in the treatment of
moderate-to-severe psoriasis. OBJECTIVE: To evaluate overall pooled study data to assess …
moderate-to-severe psoriasis. OBJECTIVE: To evaluate overall pooled study data to assess …
Long‐term safety of ustekinumab in patients with moderate‐to‐severe psoriasis: final results from 5 years of follow‐up
KA Papp, CEM Griffiths, K Gordon… - British Journal of …, 2013 - academic.oup.com
Background Long‐term safety evaluations of biologics are needed to inform patient
management decisions. Objectives To evaluate the safety of ustekinumab in patients with …
management decisions. Objectives To evaluate the safety of ustekinumab in patients with …
Ustekinumab does not increase tuberculosis risk: results from a national database in South Korea
However, South Korea has a higher tuberculosis burden than other developed countries. 4
We used the National Health Insurance Service database to select patients who were …
We used the National Health Insurance Service database to select patients who were …
Long‐term efficacy of ustekinumab in patients with moderate‐to‐severe psoriasis: results from the PHOENIX 1 trial through up to 3 years
AB Kimball, KB Gordon, S Fakharzadeh… - British Journal of …, 2012 - academic.oup.com
Background An unmet need remains for safe and effective long‐term treatments of psoriasis.
Objectives To evaluate ustekinumab efficacy and safety for up to 3 years in the PHOENIX 1 …
Objectives To evaluate ustekinumab efficacy and safety for up to 3 years in the PHOENIX 1 …
An update on the long-term safety experience of ustekinumab: results from the psoriasis clinical development program with up to four years of follow-up.
K Reich, KA Papp, CE Griffiths, PO Szapary… - Journal of drugs in …, 2012 - europepmc.org
Background The efficacy and safety profile of ustekinumab with up to three years of
exposure suggested a favorable benefit-risk profile in patients with moderate to severe …
exposure suggested a favorable benefit-risk profile in patients with moderate to severe …
Efficacy and safety of ustekinumab for the treatment of moderate-to-severe psoriasis: a phase III, randomized, placebo-controlled trial in Taiwanese and Korean …
TF Tsai, JC Ho, M Song, P Szapary, C Guzzo… - Journal of …, 2011 - Elsevier
BACKGROUND: Ustekinumab has been evaluated in Caucasian patients with psoriasis, but
no studies have been conducted in Asian patients. OBJECTIVE: To assess the efficacy and …
no studies have been conducted in Asian patients. OBJECTIVE: To assess the efficacy and …
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind …
KA Papp, RG Langley, M Lebwohl, GG Krueger… - The Lancet, 2008 - thelancet.com
Background Ustekinumab, a human monoclonal antibody against interleukins 12 and 23,
has shown therapeutic potential for psoriasis. This study assessed the efficacy and safety of …
has shown therapeutic potential for psoriasis. This study assessed the efficacy and safety of …