The effects of tempol on cyclophosphamide‐induced oxidative stress in rat micturition reflexes

EJ Gonzalez, A Peterson, S Malley… - The Scientific World …, 2015 - Wiley Online Library
We hypothesized that cyclophosphamide‐(CYP‐) induced cystitis results in oxidative stress
and contributes to urinary bladder dysfunction. We determined (1) the expression of …

Uroprotective effect of ambroxol in cyclophosphamide-induced cystitis in mice

EN Barut, S Engin, B Barut, C Kaya… - … Urology and Nephrology, 2019 - Springer
Purpose Hemorrhagic cystitis (HC) is defined as any types of acute or chronic inflammation
of urinary bladder with several reasons. One of the most common causes of HC is …

[PDF][PDF] Functional, histological structure and mastocytes alterations in rat urinary bladders following acute and chronic cyclophosphamide treatment

K Juszczak, K Gil, M Wyczolkowski… - Journal of Physiology and …, 2010 - jpp.krakow.pl
Neurogenic inflammation is linked to urinary bladder overactivity development.
Cyclophosphamide (CYP) damages all mucosal defence lines of urinary bladder and …

Effects of ozone therapy on cyclophosphamide-induced urinary bladder toxicity in rats

S Tasdemir, C Tasdemir, N Vardi, B Ates… - Clinical and …, 2013 - utpjournals.press
Purpose This study investigated the efficacy of ozone therapy (OT) in a rat model of
cyclophosphamide-induced hemorrhagic cystitis (HC). Methods Forty Wistar Albino male …

Alpha‐tocopherol, beta‐carotene and melatonin administration protects cyclophosphamide‐induced oxidative damage to bladder tissue in rats

S Sadir, S Deveci, A Korkmaz… - Cell Biochemistry and …, 2007 - Wiley Online Library
Cyclophosphamide (CP) has potential urotoxicity such as hemorrhagic cystitis (HC). 2‐
Mercaptoethane sulfonate (mesna) has been widely used as an effective agent against CP …

Inhibition of nitric oxide synthase prevents muscarinic and purinergic functional changes and development of cyclophosphamide‐induced cystitis in the rat

P Aronsson, R Vesela, M Johnsson… - BioMed research …, 2014 - Wiley Online Library
Nitric oxide (NO) has pivotal roles in cyclophosphamide‐(CYP‐) induced cystitis during
which mucosal nitric oxide synthase (NOS) and muscarinic M5 receptor expressions are …

Effect of intravesical nitric oxide therapy on cyclophosphamide-induced cystitis

H OZAWA, MB CHANCELLOR, SUKY JUNG… - The Journal of …, 1999 - auajournals.org
Purpose: This study was conducted to examine effects of nitric oxide (NO) donors on bladder
hyperactivity induced by cyclophosphamide (CYP)-induced cystitis. Materials and Methods …

Hidrox® and Chronic Cystitis: Biochemical Evaluation of Inflammation, Oxidative Stress, and Pain

R D'Amico, A Trovato Salinaro, M Cordaro, R Fusco… - Antioxidants, 2021 - mdpi.com
Interstitial cystitis/painful bladder syndrome (IC/PBS) is a chronic bladder condition
characterized by frequent urination, inflammation, oxidative stress, and pain. The aim of the …

Improvement by phytotherapeutic agent of detrusor overactivity, down-regulation of pharmacological receptors and urinary cytokines in rats with cyclophosphamide …

S Nasrin, E Masuda, H Kugaya, Y Ito, S Yamada - The Journal of urology, 2013 - Elsevier
PURPOSE: We characterized pharmacological effects of the phytotherapeutic agent
Eviprostat® on urodynamic parameters, bladder muscarinic and purinergic receptors, and …

Rho kinase inhibition ameliorates cyclophosphamide-induced cystitis in rats

A Wróbel, U Doboszewska, E Rechberger… - Naunyn-schmiedeberg's …, 2017 - Springer
Hemorrhagic cystitis often develops in patients treated with cyclophosphamide (CYP).
Studies have indicated that Rho kinase (ROCK) inhibitors may suppress detrusor …