Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies

M den Hoed, U Ekelund, S Brage, A Grontved… - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Large-scale genome-wide association (GWA) studies have thus far identified
16 loci incontrovertibly associated with obesity-related traits in adults. We examined …

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

JP Bradfield, S Vogelezang, JF Felix… - Human molecular …, 2019 - academic.oup.com
Although hundreds of genome-wide association studies-implicated loci have been reported
for adult obesity-related traits, less is known about the genetics specific for early-onset …

[PDF][PDF] Association of obesity susceptibility gene variants with metabolic syndrome and related traits in 1,443 Czech adolescents

L Dusatkova, H Zamrazilová, B Sedlackova… - Folia …, 2013 - researchgate.net
Original Article Association of Obesity Susceptibility Gene Variants with Metabolic Syndrome
and Related Traits in 1,443 Czech A Page 1 Original Article Association of Obesity Susceptibility …

Developments in obesity genetics in the era of genome-wide association studies

FR Day, RJF Loos - Lifestyle Genomics, 2011 - karger.com
Obesity is an important factor contributing to the global burden of morbidity and mortality. By
identifying obesity susceptibility genes, scientists aim to elucidate some of its aetiology …

Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

S Hägg, A Ganna, SW Van Der Laan… - Human molecular …, 2015 - academic.oup.com
To date, genome-wide association studies (GWASs) have identified> 100 loci with single
variants associated with body mass index (BMI). This approach may miss loci with high …

Association of common variants identified by recent genome-wide association studies with obesity in Chinese children: a case-control study

HJ Wang, A Hinney, JY Song, A Scherag, XR Meng… - BMC medical …, 2016 - Springer
Background Large-scale genome-wide association studies have identified multiple genetic
variants that are associated with elevated body mass index (BMI) or the risk of obesity in …

A genome-wide association meta-analysis identifies new childhood obesity loci

Nature genetics, 2012 - nature.com
Multiple genetic variants have been associated with adult obesity and a few with severe
obesity in childhood; however, less progress has been made in establishing genetic …

Genetics of childhood obesity

J Zhao, SFA Grant - Journal of obesity, 2011 - Wiley Online Library
Obesity is a major health problem and an immense economic burden on the health care
systems both in the United States and the rest of the world. The prevalence of obesity in …

The role of obesity‐associated loci identified in genome‐wide association studies in the determination of pediatric BMI

J Zhao, JP Bradfield, M Li, K Wang, H Zhang, CE Kim… - …, 2009 - Wiley Online Library
The prevalence of obesity in children and adults in the United States has increased
dramatically over the past decade. Besides environmental factors, genetic factors are known …

Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity

YF Pei, L Zhang, Y Liu, J Li, H Shen… - Human molecular …, 2014 - academic.oup.com
Obesity is a major public health problem with strong genetic determination. Multiple genetic
variants have been implicated for obesity by conducting genome-wide association (GWA) …