To maintain homeostasis, the human body employs many physiological adaptations. One of
these is maintaining an acid-base balance. In the absence of pathological states, the pH of …

Recent advances in acid–base physiology and in the epidemiology of acid–base disorders
have refined our understanding of the basic control mechanisms that determine blood pH in …

Physiological Approach to Assessment of Acid–Base Disturbances | New England Journal of
Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Stewart and beyond: New models of acid-base balance. The Henderson-Hasselbalch
equation and the base excess have been used traditionally to describe the acid-base …

Background: Disorders of acid-base involve the complex interplay of many organ systems
including brain, lungs, kidney, and liver. Compensations for acid-base disturbances within …

Background: Intensivists spend much of their time managing problems related to fluids,
electrolytes, and blood pH. Recent advances in the understanding of acid-base physiology …

Under normal physiologic conditions, acid–base balance is maintained by renal excretion of
hydrogen ions generated during the metabolism of dietary protein and other metabolic …

An advanced understanding of acid–base physiology is as central to the practice of critical
care medicine, as are an understanding of cardiac and pulmonary physiology. Intensivists …

Acid-base abnormalities are extremely common in modern ICUs. Although most cases are
mild and self-limiting, there are certain circumstances in which acid-base derangements are …

Acid–base homeostasis exerts a major influence on protein function, thereby critically
affecting tissue and organ performance. Deviations of systemic acidity in either direction can …