Background The clinical significance of coronary-artery stenoses of moderate severity can
be difficult to determine. Myocardial fractional flow reserve (FFR) is a new index of the …

Fractional flow reserve (FFR) is an invasive procedure used during coronary angiography to
determine the functional significance of coronary stenoses. Its use is particularly helpful in …

Background: In patients with coronary artery disease, clinical outcome depends on the
extent of reversible myocardial ischemia. Whether the outcome also depends on the severity …

Objectives: The purpose of this study was to investigate the relationship between
angiographic and functional severity of coronary artery stenoses in the FAME (Fractional …

Background Fractional flow reserve (FFR), defined as the ratio of maximum flow in the
presence of a stenosis to normal maximum flow, is a lesion-specific index of stenosis …

Background—Discordance between fractional flow reserve (FFR) and coronary flow velocity
reserve (CFVR) may reflect important coronary pathophysiology but usually remains …

Background—Coronary blood flow occurs mainly during the diastolic phase of each cardiac
cycle and is mainly dependent on diastolic driving pressure, especially in the left anterior …

Coronary lesions of intermediate severity often cause ischemia, and fractional flow reserve
(FFR)-guided revascularization for these coronary lesions is safe and effective. FFR derived …

Fractional flow reserve (FFR) is considered nowadays as the gold standard for invasive
assessment of physiologic stenosis significance and an indispensable tool for decision …

Aims The present analysis addresses the potential clinical and physiologic significance of
discordance in severity of coronary artery disease between the angiogram and fractional …