Background Intranasal corticosteroid irrigations, especially budesonide, are used
increasingly in the management of chronic rhinosinusitis. In post–endoscopic sinus surgery …

Background Although the safety of topical nasal steroids is well established for nasal spray
forms, data regarding the safety of steroid irrigations is limited. We studied the effect of long …

Background Chronic rhinosinusitis (CRS) has previously been thought to occur secondary to
infectious or obstructive etiologies. However, in recent years, primary CRS has been more …

Background Off‐label high‐volume sinonasal budesonide irrigations are commonly used
during the management of chronic rhinosinusitis (CRS). Although short‐term use (4 to 8 …

Background Nasal steroids play an important role in the postoperative management of
patients with chronic rhinosinusitis (CRS). However, commercially available nasal steroid …

Background Budesonide high-volume saline irrigations (HVSIs) are routinely used to treat
chronic rhinosinusitis (CRS) due to improved sinonasal delivery and efficacy compared to …

Background Recently, topical steroid therapy delivery using high‐volume sinonasal
irrigations has been used more frequently, following endoscopic sinus surgery (ESS), to …

Background Persistent mucosal inflammation in patients with chronic rhinosinusitis (CRS)
often results in ongoing symptoms, recurrence of polypoid mucosa, infective exacerbations …

Background The delivery of topical intranasal corticosteroid sprays has traditionally been the
primary method of treating recurrent nasal polyposis. An emerging treatment for polyposis is …

Objectives Budesonide nasal irrigation was introduced recently for postoperative
management of patients with chronic rhinosinusitis. The safety and therapeutic effectiveness …