Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysis
AC Ford, WJ Sandborn, KJ Khan… - Official journal of the …, 2011 - journals.lww.com
OBJECTIVES: Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory disorders
of the gastrointestinal tract of unknown etiology. Evidence for treatment of the condition with …
of the gastrointestinal tract of unknown etiology. Evidence for treatment of the condition with …
Optimizing the use of biological therapy in patients with inflammatory bowel disease
AC Moss - Gastroenterology report, 2015 - academic.oup.com
Biological therapy revolutionized the treatment of inflammatory bowel disease (IBD) during
the last decade. These monoclonal antibodies, which target tumor necrosis factor (TNF) …
the last decade. These monoclonal antibodies, which target tumor necrosis factor (TNF) …
Treatment pathways leading to biologic therapies for ulcerative colitis and Crohn's disease in the United States
CA Siegel, F Yang, S Eslava, Z Cai - Clinical and Translational …, 2020 - journals.lww.com
OBJECTIVES: Biologic therapies have been available for inflammatory bowel disease for>
20 years, but patient outcomes have not changed appreciably over this time period. To …
20 years, but patient outcomes have not changed appreciably over this time period. To …
Patients enrolled in randomized controlled trials do not represent the inflammatory bowel disease patient population
C Ha, TA Ullman, CA Siegel, A Kornbluth - Clinical gastroenterology and …, 2012 - Elsevier
BACKGROUND & AIMS: Multiple randomized controlled trials (RCTs) have been conducted
to determine therapeutic efficacy of the biological agents for the inflammatory bowel …
to determine therapeutic efficacy of the biological agents for the inflammatory bowel …
Biologics in inflammatory bowel disease: what are the data?
J Côté-Daigneault, M Bouin, R Lahaie… - United European …, 2015 - journals.sagepub.com
Background Over the last decade, biologics have gained an important place for the
treatment of moderate to severe inflammatory bowel disease (IBD), and many randomized …
treatment of moderate to severe inflammatory bowel disease (IBD), and many randomized …
Comparative efficacy of biologic therapy in biologic-naive patients with Crohn disease: a systematic review and network meta-analysis
Objective To study the comparative efficacy of biologic therapy in the management of
biologic-naïve patients with Crohn disease (CD). Patients and Methods We conducted a …
biologic-naïve patients with Crohn disease (CD). Patients and Methods We conducted a …
Biological therapies in inflammatory bowel disease: Beyond anti-TNF therapies
The pharmacological management of inflammatory bowel disease (IBD) over the last two
decades has transitioned from reliance on aminosalycilates, corticosteroids and …
decades has transitioned from reliance on aminosalycilates, corticosteroids and …
Adverse effects of biologics used for treating IBD
In the last decade, biologic agents, in particular anti-TNF agents such as infliximab,
adalimumab, and certolizumab have substantially extended the therapeutic armamentarium …
adalimumab, and certolizumab have substantially extended the therapeutic armamentarium …
Comparative effectiveness of immunosuppressants and biologics for inducing and maintaining remission in Crohn's disease: a network meta-analysis
GS Hazlewood, A Rezaie, M Borman, R Panaccione… - Gastroenterology, 2015 - Elsevier
Background & Aims There is controversy regarding the best treatment for patients with
Crohn's disease because of the lack of direct comparative trials. We compared therapies for …
Crohn's disease because of the lack of direct comparative trials. We compared therapies for …
remission rates achievable by current therapies for inflammatory bowel disease
L Peyrin‐Biroulet, M Lémann - Alimentary pharmacology & …, 2011 - Wiley Online Library
Aliment Pharmacol Ther 2011; 33: 870–879 Summary Background New medical therapies
have improved outlook in inflammatory bowel disease but published impact on surgical …
have improved outlook in inflammatory bowel disease but published impact on surgical …
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