Purpose: To prospectively compare pulmonary function tests and helical computed
tomographic (CT) indexes for quantifying pulmonary emphysema with macroscopic and …

Rationale and Objectives. Efforts to establish a quantitative approach to the computed
tomography (CT)-based characterization of the lung parenchyma in interstitial lung disease …

Pulmonary emphysema is a pathological diagnosis. The clinical diagnosis of emphysema
can be difficult because correlations between results of lung function tests and the extent of …

Purpose To prospectively investigate the effect of submaximal inspiration on computed
tomographic (CT) indexes used to quantify emphysema and to discriminate between effects …

The use of high resolution computed tomography (HRCT) for evaluating the lung
parenchyma requires an understanding of normal lung anatomy and the pathologic …

RATIONALE AND OBJECTIVES: High-resolution computed tomography (CT) measurements
of emphysema typically use Hounsfield unit (HU) density histogram thresholds or observer …

Rationale: The rate of decline of lung function is greater than age-related change in a
substantial proportion of patients with chronic obstructive pulmonary disease, even after …

Lung diseases are increasing in prevalence and overall burden worldwide. To stem the tide,
more and more national and international guidelines are recommending the use of various …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease having small
airway inflammation, emphysema, and pulmonary hypertension. It is now clear that …

We used a CT program “density mask” outlining areas with attenuation values less than—
910 HU, to indicate areas of emphysema on a chest CT and to provide an overall …