Current insights into the pathophysiology of irritable bowel syndrome

I Schwetz, S Bradesi, EA Mayer - Current gastroenterology reports, 2003 - Springer
Recent reports have emphasized the possible role of mucosal immune activation and
inflammation in neuropathic changes in the pathophysiology of irritable bowel syndrome …

The pathophysiology of irritable bowel syndrome.

I Schwetz, S Bradesi, EA Mayer - Minerva medica, 2004 - europepmc.org
Recent studies have provided evidence to suggest a possible role for mucosal immune
activation in the pathophysiology of irritable bowel syndrome (IBS). On the other hand, novel …

Abdominal pain in irritable bowel syndrome: a review of putative psychological, neural and neuro-immune mechanisms

S Elsenbruch - Brain, behavior, and immunity, 2011 - Elsevier
Chronic abdominal pain is a common symptom of great clinical significance in several areas
of medicine. In many cases no organic cause can be established resulting in the …

Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Neural and neuro-immune mechanisms of visceral hypersensitivity in irritable bowel syndrome

B Feng, JH La, ES Schwartz… - American Journal of …, 2012 - journals.physiology.org
Irritable bowel syndrome (IBS) is characterized as functional because a pathobiological
cause is not readily apparent. Considerable evidence, however, documents that sensitizing …

the psychoneuroimmunology of irritable bowel syndrome–an exploration of interactions between psychological, neurological and immunological observations

N Arebi, S Gurmany, D Bullas, A Hobson… - Alimentary …, 2008 - Wiley Online Library
Background The pathogenesis of irritable bowel syndrome (IBS) is founded on interactive
mechanisms. Disentangling these processes is a prerequisite for the development of …

Mechanisms underlying visceral hypersensitivity in irritable bowel syndrome

G Barbara, C Cremon, R De Giorgio, G Dothel… - Current …, 2011 - Springer
Visceral hypersensitivity is currently considered a key pathophysiological mechanism
involved in pain perception in large subgroups of patients with functional gastrointestinal …

Basic pathophysiologic mechanisms in irritable bowel syndrome

EA Mayer, BD Naliboff, L Chang - Digestive Diseases, 2001 - karger.com
Converging evidence supports the concept that the irritable bowel syndrome (IBS) symptom
complex results from altered regulation of gastrointestinal motility and epithelial function, as …

Brain and gut interactions in irritable bowel syndrome: new paradigms and new understandings

E Coss-Adame, SSC Rao - Current gastroenterology reports, 2014 - Springer
Irritable bowel syndrome (IBS) is characterized by abdominal pain and altered bowel habits.
Visceral hypersensitivity is believed to be a key underlying mechanism that causes pain …

Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Methods to assess visceral hypersensitivity in irritable bowel syndrome

D Keszthelyi, FJ Troost… - American Journal of …, 2012 - journals.physiology.org
Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder,
characterized by recurrent abdominal pain or discomfort in combination with disturbed …

New pathophysiological mechanisms in irritable bowel syndrome

G Barbara, R De Giorgio, V Stanghellini… - Alimentary …, 2004 - Wiley Online Library
Irritable bowel syndrome (IBS) is a functional, multifactorial disease characterized by
abdominal pain and erratic bowel habit. Changes in gastrointestinal motor function …