We reported that the generation of nitric oxide by mitochondria is catalyzed by a constitutive,
mitochondrial nitric-oxide synthase (mtNOS). Given that this production may establish the …

Nitric oxide is a potent modulator of mitochondrial respiration, ATP synthesis, and KATP
channel activity. Recent studies show the presence of a potentionally new isoform of the …

Different mitochondrial nitric-oxide synthase (mtNOS) isoforms have been described in rat
and mouse tissues, such as liver, thymus, skeletal muscle, and more recently, heart and …

Recent studies indicated that there is a distinct mitochondrial nitric oxide synthase (mtNOS)
enzyme, which may be identical to the other known NOS isoforms. We investigated the …

The effect of O2 concentration on mitochondrial nitric oxide synthase (mtNOS) activity and
on O2− production was determined in rat liver, brain, and kidney submitochondrial …

In this article we demonstrate the immunocytochemical localization of nitric oxide synthase
in mitochondria isolated from heart, skeletal muscle, and kidney, using a monoclonal …

Nitric oxide is generated in vivo by nitric-oxide synthase (NOS) during the conversion of L-
Arg to citrulline. Using a variety of biological systems and approaches emerging evidence …

The biosynthesis of nitric oxide (NO⋅) in different cell types occurs concomitantly with the
conversion ofl-arginine to l-citrulline by the enzyme nitric-oxide synthase (NOS). NO⋅ has …

Nitric oxide (NO) can bind to and inhibit the terminal enzyme of the mitochondrial respiratory
chain, cytochrome c oxidase (complex IV). In vivo, NO is made by the NO synthase (NOS) …

Nitric oxide (NO) is synthesized by members of the NO synthase (NOS) family. Recently the
existence of a mitochondrial NOS (mtNOS), its Ca 2+ dependence, and its relevance for …