Adenosine receptors and their ligands
KN Klotz - Naunyn-Schmiedeberg's archives of pharmacology, 2000 - Springer
The regulatory actions of adenosine are mediated via four subtypes of G protein-coupled
receptors distinguished as A 1, A 2A, A 2B and A 3 receptors. Their presence on basically …
receptors distinguished as A 1, A 2A, A 2B and A 3 receptors. Their presence on basically …
Adenosine receptors: new opportunities for future drugs
SA Poulsen, RJ Quinn - Bioorganic & medicinal chemistry, 1998 - Elsevier
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Adenosine receptors and their modulators
The identification and characterization of adenosine receptors and the development of
potent, receptor subtype-selective agonist and antagonists has been an active area of …
potent, receptor subtype-selective agonist and antagonists has been an active area of …
Structure and function of adenosine receptors and their genes
BB Fredholm, G Arslan, L Halldner, B Kull… - Naunyn-Schmiedeberg's …, 2000 - Springer
Four adenosine receptors have been cloned from many mammalian and some non-
mammalian species. In each case the translated part of the receptor is encoded by two …
mammalian species. In each case the translated part of the receptor is encoded by two …
Comparative pharmacology of human adenosine receptor subtypes–characterization of stably transfected receptors in CHO cells
KN Klotz, J Hessling, J Hegler, C Owman, B Kull… - Naunyn-Schmiedeberg's …, 1997 - Springer
Four adenosine receptor subtypes of the family of G protein-coupled receptors, designated A
1, A 2A, A 2B and A 3 are currently known. In this study all human subtypes were stably …
1, A 2A, A 2B and A 3 are currently known. In this study all human subtypes were stably …
Adenosine receptor ligands-recent developments part I. Agonists
CE Muller - Current medicinal chemistry, 2000 - ingentaconnect.com
Developments in the field of adenosine receptor (AR) agonists of the past years are
presented and discussed. Four different AR subtypes, A1, A2A, A2B, and A3, have been …
presented and discussed. Four different AR subtypes, A1, A2A, A2B, and A3, have been …
Progress in the pursuit of therapeutic adenosine receptor antagonists
S Moro, ZG Gao, KA Jacobson… - Medicinal research …, 2006 - Wiley Online Library
Ever since the discovery of the hypotensive and bradycardiac effects of adenosine,
adenosine receptors continue to represent promising drug targets. First, this is due to the fact …
adenosine receptors continue to represent promising drug targets. First, this is due to the fact …
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors—an update
BB Fredholm, AP IJzerman, KA Jacobson… - Pharmacological …, 2011 - ASPET
In the 10 years since our previous International Union of Basic and Clinical Pharmacology
report on the nomenclature and classification of adenosine receptors, no developments …
report on the nomenclature and classification of adenosine receptors, no developments …
Pharmacology of adenosine receptors: the state of the art
Adenosine is a ubiquitous endogenous autacoid whose effects are triggered through the
enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Due to the rapid …
enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Due to the rapid …
Medicinal chemistry of adenosine A3 receptor ligands
CE Muller - Current topics in medicinal chemistry, 2003 - ingentaconnect.com
A3 Adenosine receptors (ARs) exhibit large species differences. Potent, selective agonists
for rat (eg Cl-IB-MECA, 5) and human A3 ARs (eg PENECA, 17, and analogs) have been …
for rat (eg Cl-IB-MECA, 5) and human A3 ARs (eg PENECA, 17, and analogs) have been …