The regulatory actions of adenosine are mediated via four subtypes of G protein-coupled
receptors distinguished as A 1, A 2A, A 2B and A 3 receptors. Their presence on basically …

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The identification and characterization of adenosine receptors and the development of
potent, receptor subtype-selective agonist and antagonists has been an active area of …

Four adenosine receptors have been cloned from many mammalian and some non-
mammalian species. In each case the translated part of the receptor is encoded by two …

Four adenosine receptor subtypes of the family of G protein-coupled receptors, designated A
1, A 2A, A 2B and A 3 are currently known. In this study all human subtypes were stably …

Developments in the field of adenosine receptor (AR) agonists of the past years are
presented and discussed. Four different AR subtypes, A1, A2A, A2B, and A3, have been …

Ever since the discovery of the hypotensive and bradycardiac effects of adenosine,
adenosine receptors continue to represent promising drug targets. First, this is due to the fact …

In the 10 years since our previous International Union of Basic and Clinical Pharmacology
report on the nomenclature and classification of adenosine receptors, no developments …

Adenosine is a ubiquitous endogenous autacoid whose effects are triggered through the
enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Due to the rapid …

A3 Adenosine receptors (ARs) exhibit large species differences. Potent, selective agonists
for rat (eg Cl-IB-MECA, 5) and human A3 ARs (eg PENECA, 17, and analogs) have been …