Novel R-(+)-limonene-based thiosemicarbazones and their antitumor activity against human tumor cell lines

F Vandresen, H Falzirolli, SAA Batista… - European journal of …, 2014 - Elsevier
In an attempt to develop potent and selective antitumor agents, a series of novel
thiosemicarbazones derived from a natural monoterpene R-(+)-limonene was synthesized …

Synthesis and evaluation of naphthalene-based thiosemicarbazone derivatives as new anticancer agents against LNCaP prostate cancer cells

MD Altintop, B Sever, A Özdemir, G Kuş… - Journal of enzyme …, 2016 - Taylor & Francis
Fourteen new naphthalene-based thiosemicarbazone derivatives were designed as
anticancer agents against LNCaP human prostate cancer cells and synthesized. MTT assay …

[HTML][HTML] Synthesis and cytotoxicity evaluation of thiosemicarbazones and their thiazole derivatives

SFP Braga, NC Fonseca, JP Ramos… - Brazilian Journal of …, 2016 - SciELO Brasil
The aims of this study were to synthesize a series of thiosemicarbazones and their thiazole
derivatives, to investigate their cytotoxic activity against three human cancers and normal …

Synthesis and antiproliferative activity of novel symmetrical alkylthio-and alkylseleno-imidocarbamates

E Ibáñez, D Plano, M Font, A Calvo, C Prior… - European journal of …, 2011 - Elsevier
The study described here concerns the synthesis of a series of thirty new symmetrically
substituted imidothiocarbamate and imidoselenocarbamate derivatives and their evaluation …

Novel thiosemicarbazone derivatives as potential antitumor agents: Synthesis, physicochemical and structural properties, DNA interactions and antiproliferative …

I Đilović, M Rubčić, V Vrdoljak, SK Pavelić… - Bioorganic & medicinal …, 2008 - Elsevier
The paper describes synthesis of several novel thiosemicarbazone derivatives. Furthermore,
crystal and molecular structure of 4-diethylamino-salicylaldehyde 4 …

Synthesis and anticancer activity of thiosemicarbazones

W Hu, W Zhou, C Xia, X Wen - Bioorganic & medicinal chemistry letters, 2006 - Elsevier
Twenty-six thiosemicarbazones (III-1–III-26) were synthesized via three steps starting from
hydrazine hydrate and carbon disulfide. The testing of anticancer activity of these …

Thiosemicarbazones as potent anticancer agents and their modes of action

B Shakya, PN Yadav - Mini Reviews in Medicinal Chemistry, 2020 - ingentaconnect.com
Thiosemicarbazones (TSCs) are a class of Schiff bases usually obtained by the
condensation of thiosemicarbazide with a suitable aldehyde or ketone. TSCs have been the …

Thiazole-based thiosemicarbazones: Synthesis, cytotoxicity evaluation and molecular docking study

SM Gomha, HA Abdelhady, DZH Hassain… - Drug design …, 2021 - Taylor & Francis
Introduction Hybrid drug design has developed as a prime method for the development of
novel anticancer therapies that can theoretically solve much of the pharmacokinetic …

Synthesis of thiophene-thiosemicarbazone derivatives and evaluation of their in vitro and in vivo antitumor activities

JF de Oliveira, AL da Silva… - European journal of …, 2015 - Elsevier
A series of thiophene-2-thiosemicarbazones derivatives (5–14) was synthesized,
characterized and evaluated for their antitumor activity. They were tested in vitro against …

[HTML][HTML] Synthesis, structural elucidation and cytotoxicity of new thiosemicarbazone derivatives

MA Hussein, MA Iqbal, MI Umar, RA Haque… - Arabian Journal of …, 2019 - Elsevier
Abstract Syntheses and characterization (1 H & 13 C NMR and CHN) of four new
thiosemicarbazone derivatives (1–4) are reported. The molecular structures of compounds 1 …