Ageing processes play a major contributing role for the development of Osteoarthritis (OA).
This prototypic degenerative condition of ageing is the most common form of arthritis and is …

Aging is a natural process by which every single living organism approaches its twilight of
existence in a natural way. However, aging is also linked to the pathogenesis of a number of …

OBJECTIVE: Age-related changes in multiple components of the musculoskeletal system
may contribute to the well established link between aging and osteoarthritis (OA). This …

Aging and inflammation are major contributing factors to the development and progression
of arthritic and musculoskeletal diseases.“Inflammaging” refers to low-grade inflammation …

Osteoarthritis (OA) is the most common joint disease that causes pain and disability in the
adult population. OA is primarily caused by trauma induced by an external force or by age …

The extracellular matrix of articular cartilage is the primary target of osteoarthritic cartilage
degradation. However, cartilage cells have a pivotal role during osteoarthritis, as they are …

Adult articular chondrocytes undergo slow senescence and dedifferentiation during in vitro
expansion, restricting successful cartilage regeneration. A complete understanding of the …

Aging is a major risk factor for osteoarthritis and osteoporosis. Yet, these are not necessary
outcomes of aging, and the relationship between age-related changes in bone and cartilage …

There has been considerable advancement over the last few years in the treatment of
osteoarthritis, common chronic disease and a major cause of disability in older adults. In this …

Osteoarthritis (OA) is associated with articular cartilage abnormalities and affects people of
older age: preventative or therapeutic treatment measures for OA and related articular …