Particulate systems in the form of liposomes, polymeric micelles, polymeric nano-and
microparticles, and many others offer a rational approach for selective delivery of therapeutic …

Heterogeneous functions of macrophages in human immune systems have renewed interest
in targeting of drugs to these cells. Various carrier systems have emerged to deliver drugs to …

The role of cells of the mononuclear phagocyte system (MPS), which includes the Kupffer
cells in the liver; alveolar, splenic, lymph node, and bone marrow macrophages; tissue …

Introduction: Targeted drug delivery to the macrophages appears to be an attractive
proposition to improve therapeutic efficacy of enclosed drug. Thus, macrophages can be …

As the role of monocytes and macrophages in a range of diseases is better understood,
strategies to target these cell types are of growing importance both scientifically and …

The use of non-viral nanoparticulate systems for the delivery of therapeutic agents is
receiving considerable attention for medical and pharmaceutical applications. This …

Subunit vaccination benefits from improved safety over attenuated or inactivated vaccines,
but their limited capability to elicit long-lasting, concerted cellular and humoral immune …

The rapid recognition of intravenously injected colloidal carriers, such as liposomes and
polymeric nanospheres from the blood by Kupffer cells, has initiated a surge of development …

Biomimetic approaches utilize natural cell membrane‐derived nanovesicles to camouflage
nanoparticles to circumvent some limitations of nanoscale materials. This emergent cell …

Macrophages have been extensively used in the development of drug delivery systems, as
they can prolong the circulation and release of drugs, extend their half-life, increase their …