Targeting of hepatic macrophages by therapeutic nanoparticles
CI Colino, JM Lanao, C Gutierrez-Millan - Frontiers in immunology, 2020 - frontiersin.org
Hepatic macrophage populations include different types of cells with plastic properties that
can differentiate into diverse phenotypes to modulate their properties in response to different …
can differentiate into diverse phenotypes to modulate their properties in response to different …
Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles
Identifying intended or accidental cellular targets for drug delivery systems is highly relevant
for evaluating therapeutic and toxic effects. However, limited knowledge exists on the …
for evaluating therapeutic and toxic effects. However, limited knowledge exists on the …
Physicochemical and biological aspects of macrophage‐mediated drug targeting in anti‐microbial therapy
Macrophages are important drug targets as they mediate a wide variety of infectious
diseases. Visceral leishmaniasis (VL), schistosomiasis, brucellosis, and salmonellosis are …
diseases. Visceral leishmaniasis (VL), schistosomiasis, brucellosis, and salmonellosis are …
Particle engineering to enhance or lessen particle uptake by alveolar macrophages and to influence the therapeutic outcome
The alveolar macrophages defend the lung against airborne pollutants and infectious
microorganisms. Recent advances in the understanding of the role of macrophages in …
microorganisms. Recent advances in the understanding of the role of macrophages in …
Drug delivery strategies to control macrophages for tissue repair and regeneration
R Garash, A Bajpai… - Experimental biology …, 2016 - journals.sagepub.com
Tissue repair and regeneration is a complex process. Our bodies have an excellent capacity
to regenerate damaged tissues in many situations. However, tissue healing is impaired in …
to regenerate damaged tissues in many situations. However, tissue healing is impaired in …
Macrophages as targets for delivery of liposome-encapsulated antimicrobial agents
CR Alving - Advanced Drug Delivery Reviews, 1988 - Elsevier
Macrophages are particularly effective in dealing with microorganisms that cause chronic
and intracellular infectious diseases and with organisms that have eluded killing by …
and intracellular infectious diseases and with organisms that have eluded killing by …
Micro and nanoparticle‐based delivery systems for vaccine immunotherapy: an immunological and materials perspective
J Leleux, K Roy - Advanced healthcare materials, 2013 - Wiley Online Library
The development and widespread application of vaccines has been one of the most
significant achievements of modern medicine. Vaccines have not only been instrumental in …
significant achievements of modern medicine. Vaccines have not only been instrumental in …
Transient suppression of macrophage functions by liposome-encapsulated drugs
N van Rooijen, J Bakker, N Sanders - Trends in biotechnology, 1997 - cell.com
Macrophages play an important role in host defense reactions, for example, by phagocytosis
of particulate materials. This process also results in the rapid removal of targeting devices …
of particulate materials. This process also results in the rapid removal of targeting devices …
Particulate delivery systems for vaccines: what can we expect?
VW Bramwell, Y Perrie - Journal of pharmacy and …, 2006 - Wiley Online Library
In our attempts to thwart the unwanted attentions of microbes by prophylactic and
therapeutic vaccination, the knowledge of interactions at the molecular level may prove to be …
therapeutic vaccination, the knowledge of interactions at the molecular level may prove to be …
Nanoparticle internalization promotes the survival of primary macrophages
Macrophages, a class of tissue resident innate immune cells, are responsible for
sequestering foreign objects through the process of phagocytosis, making them a promising …
sequestering foreign objects through the process of phagocytosis, making them a promising …