Transient suppression of macrophage functions by liposome-encapsulated drugs

N van Rooijen, J Bakker, N Sanders - Trends in biotechnology, 1997 - cell.com
Macrophages play an important role in host defense reactions, for example, by phagocytosis
of particulate materials. This process also results in the rapid removal of targeting devices …

Nanoparticles to target and treat macrophages: the Ockham's concept?

M Medrano-Bosch, A Moreno-Lanceta… - Pharmaceutics, 2021 - mdpi.com
Nanoparticles are nanomaterials with three external nanoscale dimensions and an average
size ranging from 1 to 1000 nm. Nanoparticles have gained notoriety in technological …

Polymeric micro-and nanoparticles for immune modulation

E Ben-Akiva, SE Witte, RA Meyer, KR Rhodes… - Biomaterials …, 2019 - pubs.rsc.org
New advances in biomaterial-based approaches to modulate the immune system are being
applied to treat cancer, infectious diseases, and autoimmunity. Particulate systems are …

Engineering nanoparticles to overcome barriers to immunotherapy

R Toy, K Roy - Bioengineering & translational medicine, 2016 - Wiley Online Library
Advances in immunotherapy have led to the development of a variety of promising
therapeutics, including small molecules, proteins and peptides, monoclonal antibodies, and …

Use of nanoformulation to target macrophages for disease treatment

X Liu, X Xie, J Jiang, M Lin, E Zheng… - Advanced Functional …, 2021 - Wiley Online Library
Macrophages are abundant immune cells, which serve as a primary cell population capable
of interacting with foreign substances, including engineered nanomaterials (NMs). In …

Cell delivery of therapeutic nanoparticles

JE McMillan, E Batrakova, HE Gendelman - Progress in molecular biology …, 2011 - Elsevier
Nanomedicine seeks to manufacture drugs and other biologically relevant molecules that
are packaged into nanoscale systems for improved delivery. This includes known drugs …

Improving selective targeting to macrophage subpopulations through modifying liposomes with arginine based materials

L Ma, HC Bygd, KM Bratlie - Integrative Biology, 2017 - academic.oup.com
The effects of surface modifications on liposomes using a library of arginine derivatives for
improved drug delivery were examined. Both unmodified and modified liposomes were …

Engineering nano‐and microparticles to tune immunity

JJ Moon, B Huang, DJ Irvine - Advanced materials, 2012 - Wiley Online Library
The immune system can be a cure or cause of disease, fulfilling a protective role in attacking
cancer or pathogenic microbes but also causing tissue destruction in autoimmune disorders …

Harnessing anti‐tumor and tumor‐tropism functions of macrophages via nanotechnology for tumor immunotherapy

Y Zheng, Y Han, Q Sun, Z Li - Exploration, 2022 - Wiley Online Library
Reprogramming the immunosuppressive tumor microenvironment by modulating
macrophages holds great promise in tumor immunotherapy. As a class of professional …

Macrophage membrane coated nanoparticles: a biomimetic approach for enhanced and targeted delivery

N Khatoon, Z Zhang, C Zhou, M Chu - Biomaterials science, 2022 - pubs.rsc.org
The enhanced and targeted drug delivery with low systemic toxicity and subsequent release
of drugs is a major concern among researchers and pharmaceutics. In spite of greater …