Macrophages are widely distributed in many tissues of the body including lympho-
haemotopoietic organs, skin, gut, other portals of entry and the nervous system. They are …

Currently used pharmaceutical nanocarriers, such as liposomes, micelles, nanoemulsions,
polymeric nanoparticles and many others demonstrate a broad variety of useful properties …

Uncontrolled inflammation is a major pathological factor underlying a range of diseases
including autoimmune conditions, cardiovascular disease, and cancer. Improving localized …

Introduction Macrophages are involved in the normal defense of the body; however, the
varying phenotypes of macrophages and imbalance in their ratio lead to the impairment of …

An overview of recent advances in the surface modification of colloidal particles to oppose
uptake by the mononuclear phagocyte system (MPS) is presented. First, we describe the …

Successful homing of drugs to the desired biological compartment of the host usually
depends on the intrinsic properties of the drug molecules. However, it can always be …

A deeper understanding of how the physical properties of particles regulate specific
biological responses is becoming a crucial requirement for their successful biomedical …

Macrophages play a key role in defending against foreign pathogens, healing wounds, and
regulating tissue homeostasis. Driving this versatility is their phenotypic plasticity, which …

Biodegradable microparticles represent a promising carrier system for the efficient delivery
of therapeutic macromolecules to phagocytic professional antigen-presenting cells (APC) …

Macrophages are cells of the innate immune system that are resident in all tissues, including
metabolic organs such as the liver and adipose tissue (AT). Because of their phenotypic …