Detecting the molecular system signatures of idiopathic pulmonary fibrosis through integrated genomic analysis
I Gangwar, N Kumar Sharma, G Panzade, S Awasthi… - Scientific reports, 2017 - nature.com
Abstract Idiopathic Pulmonary Fibrosis (IPF) is an incurable progressive fibrotic disease of
the lungs. We currently lack a systematic understanding of IPF biology and a systems …
the lungs. We currently lack a systematic understanding of IPF biology and a systems …
Integrative analysis of lung molecular signatures reveals key drivers of idiopathic pulmonary fibrosis
SK Kim, SM Jung, KS Park, KJ Kim - BMC Pulmonary Medicine, 2021 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease with a high clinical
burden. The molecular signatures of IPF were analyzed to distinguish molecular subgroups …
burden. The molecular signatures of IPF were analyzed to distinguish molecular subgroups …
Identification of key candidate genes involved in the progression of idiopathic pulmonary fibrosis
Y Cui, J Ji, J Hou, Y Tan, X Han - Molecules, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a lethal, agnogenic interstitial lung disease with limited
therapeutic options. To investigate vital genes involved in the development of IPF, we …
therapeutic options. To investigate vital genes involved in the development of IPF, we …
Integrative analysis reveals the recurrent genetic etiologies in idiopathic pulmonary fibrosis
Background Idiopathic pulmonary fibrosis (IPF) is increasingly recognized as a chronic,
progressive and fatal lung disease with an unknown etiology. Current studies focus on …
progressive and fatal lung disease with an unknown etiology. Current studies focus on …
Cluster analysis of transcriptomic datasets to identify endotypes of idiopathic pulmonary fibrosis
Background Considerable clinical heterogeneity in idiopathic pulmonary fibrosis (IPF)
suggests the existence of multiple disease endotypes. Identifying these endotypes would …
suggests the existence of multiple disease endotypes. Identifying these endotypes would …
Integrative analyses of genes associated with idiopathic pulmonary fibrosis
H Wang, Q Xie, W Ou‐Yang… - Journal of Cellular …, 2019 - Wiley Online Library
Idiopathic pulmonary fibrosis (IPF), characterized by irreversible scarring and progressive
destruction of the lung tissue, is one of the most common types of idiopathic interstitial …
destruction of the lung tissue, is one of the most common types of idiopathic interstitial …
Gene correlation network analysis to identify regulatory factors in idiopathic pulmonary fibrosis
Background Idiopathic pulmonary fibrosis (IPF) is a severe lung disease characterised by
extensive pathological changes. The objective for this study was to identify the gene network …
extensive pathological changes. The objective for this study was to identify the gene network …
Reviews and prospectives of signaling pathway analysis in idiopathic pulmonary fibrosis
Z Yan, Z Ping - Autoimmunity reviews, 2014 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing disease with disappointing
survival rate, and uneffective therapeutic progress has been made in the last few years …
survival rate, and uneffective therapeutic progress has been made in the last few years …
Evolving genomic approaches to idiopathic pulmonary fibrosis: moving beyond genes
DJ Kass, N Kaminski - Clinical and translational science, 2011 - Wiley Online Library
A little more than 10 years ago, the completed sequencing of the human genome boldly
promised to usher in an era of enhanced understanding and accelerated development of …
promised to usher in an era of enhanced understanding and accelerated development of …
Integrative analyses for the identification of idiopathic pulmonary fibrosis-associated genes and shared loci with other diseases
Background Although genome-wide association studies (GWAS) have identified many
genomic regions associated with idiopathic pulmonary fibrosis (IPF), the causal genes and …
genomic regions associated with idiopathic pulmonary fibrosis (IPF), the causal genes and …