Candida albicans Killing by RAW 264.7 Mouse Macrophage Cells: Effects of Candida Genotype, Infection Ratios, and Gamma Interferon Treatment

A Marcil, D Harcus, DY Thomas… - Infection and …, 2002 - Am Soc Microbiol
Phagocytic cells such as neutrophils and macrophages are potential components of the
immune defense that protects mammals against Candida albicans infection. We have tested …

Production and function of cytokines in natural and acquired immunity to Candida albicans infection

RB Ashman, JM Papadimitriou - Microbiological reviews, 1995 - Am Soc Microbiol
Host resistance against infections caused by the yeast Candida albicans is mediated
predominantly by polymorphonuclear leukocytes and macrophages. Antigens of Candida …

Contribution of Candida albicans Cell Wall Components to Recognition by and Escape from Murine Macrophages

CGJ McKenzie, U Koser, LE Lewis, JM Bain… - Infection and …, 2010 - Am Soc Microbiol
The pathogenicity of the opportunistic human fungal pathogen Candida albicans depends
on its ability to escape destruction by the host immune system. Using mutant strains that are …

Early differential molecular response of a macrophage cell line to yeast and hyphal forms of Candida albicans

E Blasi, L Pitzurra, M Puliti, L Lanfrancone… - Infection and …, 1992 - Am Soc Microbiol
The dimorphic transition of Candida albicans from the yeast (Y-Candida) to the hyphal (H-
Candida) form is a complex event; the relevance of this transition in fungal pathogenicity is …

[HTML][HTML] Candida albicans infection inhibits macrophage cell division and proliferation

LE Lewis, JM Bain, C Lowes, NAR Gow… - Fungal Genetics and …, 2012 - Elsevier
The pathogenicity of the opportunistic human fungal pathogen Candida albicans depends
on its ability to inhibit effective destruction by host phagocytes. Using live cell video …

Differential susceptibility of yeast and hyphal forms of Candida albicans to macrophage-derived nitrogen-containing compounds

E Blasi, L Pitzurra, M Puliti, AR Chimienti… - Infection and …, 1995 - Am Soc Microbiol
Candida albicans is a dimorphic fungus capable of transition from the yeast form (Y-
Candida) to the hyphal form (H-Candida). Both Y-Candida and H-Candida are known to be …

Immunomodulation by a low-virulence, agerminative variant of Candida albicans. Further evidence for macrophage activation as one of the effector mechanisms of …

F Bistoni, G Verducci, S Perito… - Journal of medical …, 1988 - Taylor & Francis
Systemic infection of mice with a Candida albicans strain (PCA-2) incapable of yeast-
mycelial conversion is known to activate host macrophages and confer protection against …

In vitro study of contact-mediated killing of Candida albicans hyphae by activated murine peritoneal macrophages in a serum-free medium

T Hashimoto - Infection and immunity, 1991 - Am Soc Microbiol
Activated peritoneal macrophages obtained from Listeria-immune mice were demonstrated
to kill nonphagocytosable Candida albicans hyphae by contact-mediated mechanisms in a …

Macrophage-dependent candidacidal mechanisms in the murine system. Comparison of murine Kupffer cell and peritoneal macrophage candidacidal mechanisms.

HP Redmond, J Shou, HJ Gallagher… - … (Baltimore, Md.: 1950 …, 1993 - journals.aai.org
Candida albicans infection is common in immunocompromised patients. The role of fixed
tissue macrophages (M phi), including Kupffer cells (KC) and peritoneal macrophages (PM …

Candida albicans morphogenesis is not required for macrophage interleukin 1β production

M Wellington, K Koselny, DJ Krysan - MBio, 2013 - Am Soc Microbiol
The interaction of Candida albicans with macrophages induces the production of interleukin
1β (IL-1β) through inflammasome activation in a process that is required for host survival. C …