Impact of body weight change on clinical outcomes in patients with idiopathic pulmonary fibrosis receiving pirfenidone

TH Kim, YY Shin, HJ Kim, MJ Song, YW Kim, SY Lim… - Scientific Reports, 2022 - nature.com
There have been limited studies on the association between prognosis and body weight
change in patients with idiopathic pulmonary fibrosis (IPF). This single-center retrospective …

Clinical impact of weight loss on mortality in patients with idiopathic pulmonary fibrosis: a retrospective cohort study

JK Lee, C Chung, J Kim, HS Cho, HC Kim - Scientific Reports, 2023 - nature.com
Patients with idiopathic pulmonary fibrosis (IPF) often experience weight loss during the
follow-up period. However, the prevalence and clinical impact of weight loss in these …

Post hoc analysis of clinical outcomes in placebo-and pirfenidone-treated patients with IPF stratified by BMI and weight loss

S Jouneau, B Crestani, R Thibault, M Lederlin… - Respiration, 2022 - karger.com
Background: Weight loss is frequently reported in patients with idiopathic pulmonary fibrosis
(IPF) and may be associated with worse outcomes in these patients. Objective: The aim of …

Choice of antifibrotic medication and disease severity predict weight loss in idiopathic pulmonary fibrosis

A Perelas, J Glennie, K van Kerkhove, M Li… - Pulmonary …, 2019 - Elsevier
Purpose Although safety and tolerability of approved antifibrotics has been reported
extensively, little is known about their effects on weight. We analyzed predictors of weight …

Deterioration of high-resolution computed tomography findings predicts disease progression after initial decline in forced vital capacity in idiopathic pulmonary fibrosis …

H Higo, N Miyahara, A Taniguchi, S Senoo, J Itano… - Respiratory …, 2020 - Elsevier
Background Pirfenidone suppresses the decline of forced vital capacity (FVC) in patients
with idiopathic pulmonary fibrosis (IPF). However, IPF progresses in some patients despite …

[HTML][HTML] Efficacy of lower dose pirfenidone for idiopathic pulmonary fibrosis in real practice: a retrospective cohort study

H Hwang, JK Lee, SM Choi, YJ Lee… - The Korean Journal …, 2022 - ncbi.nlm.nih.gov
Methods This multicenter retrospective cohort study investigated 338 patients treated with
pirfenidone between July 2012 and March 2018. Demographics, pulmonary function …

Association between weight loss and mortality in idiopathic pulmonary fibrosis

A Kalininskiy, AR Rackow, D Nagel, D Croft… - Respiratory …, 2022 - Springer
Rationale Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung
disease that has no cure. Many current research efforts center on diagnostic and therapeutic …

Safety and efficacy of pirfenidone in advanced idiopathic pulmonary fibrosis: a nationwide post-marketing surveillance study in Korean patients

MP Chung, MS Park, IJ Oh, HB Lee, YW Kim… - Advances in …, 2020 - Springer
Aim The efficacy and safety of pirfenidone have been previously demonstrated in patients
with mild-to-moderate idiopathic pulmonary fibrosis (IPF). However, the effect of pirfenidone …

Factors associated with dose reduction of pirfenidone in patients with idiopathic pulmonary fibrosis: A study based on real-world clinical data

J Kim, C Chung, HS Cho, HC Kim - Plos one, 2023 - journals.plos.org
Introduction Although pirfenidone slows disease progression in patients with idiopathic
pulmonary fibrosis (IPF), in clinical practice, patients often cannot tolerate the recommended …

Body mass index and weight loss as risk factors for poor outcomes in patients with idiopathic pulmonary fibrosis: a systematic review and meta-analysis

X He, J Ji, C Liu, Z Luo, J Tang, H Yan, L Guo - Annals of Medicine, 2024 - Taylor & Francis
Objective The association between nutritional status and prognosis of idiopathic pulmonary
fibrosis (IPF) remains unclear. This systematic review and meta-analysis aimed to explore …