Background Cholesterol efflux capacity (CEC) measures the ability of high-density
lipoprotein (HDL) to remove cholesterol from atherosclerotic plaques. It is mediated by …

Background and aims Lipid-rich foam cell macrophages drive atherosclerosis via several
mechanisms, including inflammation, lipid uptake, lipid deposition and plaque vulnerability …

In chronic inflammatory diseases, cardiovascular disease risk is increased and is the main
cause of increased mortality. Oxidized LDL (oxLDL) and scavenger receptors participate in …

In the progression of atherosclerosis, macrophages are the key immune cells for foam cell
formation. During hyperlipidemic condition, phagocytic cells such as monocytes and …

Low-grade systemic inflammation is often associated with metabolic syndrome, which plays
a critical role in the development of the obesity-associated inflammatory diseases, including …

Toll-like receptor-dependent lipid body formation in macroph... : Current Opinion in Lipidology
Toll-like receptor-dependent lipid body formation in macrophage foam cell formation : Current …

Interleukin (IL)-10 may have a therapeutic potential in atherosclerosis, but its mechanisms of
action have not been clarified. Foam cell formation is a key event in atherogenesis, and …

Macrophages have a crucial role in the pathogenesis and progression of metabolic and
cardiovascular diseases, including diabetes, hypertension, atherosclerosis, and heart …

In atherosclerosis lipoproteins stimulate the innate immune response, leading to the release
of inflammatory cytokines and chemokines. Hypercholesterolemia may activate the …