AB0294 INFLAMMATION AND IMMUNOMODULATORY THERAPIES INFLUENCE THE RELATIONSHIP BETWEEN ATP-BINDING CASSETTE TRANSPORTER A1 …

G Karpouzas, B Papotti, S Ormseth, M Palumbo… - 2023 - ard.bmj.com
Background Cholesterol efflux capacity (CEC) measures the ability of high-density
lipoprotein (HDL) to remove cholesterol from atherosclerotic plaques. It is mediated by …

Macrophage polarisation associated with atherosclerosis differentially affects their capacity to handle lipids

K Baidžajevas, É Hadadi, B Lee, J Lum, F Shihui… - Atherosclerosis, 2020 - Elsevier
Background and aims Lipid-rich foam cell macrophages drive atherosclerosis via several
mechanisms, including inflammation, lipid uptake, lipid deposition and plaque vulnerability …

Blockade of IL-6 and TNF-α inhibited oxLDL-induced production of MCP-1 via scavenger receptor induction

M Hashizume, M Mihara - European journal of pharmacology, 2012 - Elsevier
In chronic inflammatory diseases, cardiovascular disease risk is increased and is the main
cause of increased mortality. Oxidized LDL (oxLDL) and scavenger receptors participate in …

[HTML][HTML] Deciphering macrophage phenotypes upon lipid uptake and atherosclerosis

J Lee, JH Choi - Immune Network, 2020 - ncbi.nlm.nih.gov
In the progression of atherosclerosis, macrophages are the key immune cells for foam cell
formation. During hyperlipidemic condition, phagocytic cells such as monocytes and …

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases

M Yu, H Zhou, J Zhao, N Xiao… - Journal of Experimental …, 2014 - rupress.org
Low-grade systemic inflammation is often associated with metabolic syndrome, which plays
a critical role in the development of the obesity-associated inflammatory diseases, including …

Toll-like receptor-dependent lipid body formation in macrophage foam cell formation

G Nicolaou, C Erridge - Current opinion in lipidology, 2010 - journals.lww.com
Toll-like receptor-dependent lipid body formation in macroph... : Current Opinion in Lipidology
Toll-like receptor-dependent lipid body formation in macrophage foam cell formation : Current …

Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms

B Halvorsen, T Wæhre, H Scholz, OP Clausen… - Journal of lipid …, 2005 - ASBMB
Interleukin (IL)-10 may have a therapeutic potential in atherosclerosis, but its mechanisms of
action have not been clarified. Foam cell formation is a key event in atherogenesis, and …

[引用][C] Targeting TLR4/MAPKs signa-ling pathway: A better option for therapeutic inhibition of atheroselerosis

JP Ayyappan, A Abraham - World, 2014

Mechanism and therapeutic potential of macrophages in metabolic and cardiovascular diseases

X Nie, Y Deng, X Tong, F Han - Frontiers in Immunology, 2023 - frontiersin.org
Macrophages have a crucial role in the pathogenesis and progression of metabolic and
cardiovascular diseases, including diabetes, hypertension, atherosclerosis, and heart …

Mast cells emerge as mediators of atherosclerosis: Special emphasis on IL-37 inhibition

P Conti, G Lessiani, SK Kritas, G Ronconi, A Caraffa… - Tissue and Cell, 2017 - Elsevier
In atherosclerosis lipoproteins stimulate the innate immune response, leading to the release
of inflammatory cytokines and chemokines. Hypercholesterolemia may activate the …