AB0294 INFLAMMATION AND IMMUNOMODULATORY THERAPIES INFLUENCE THE RELATIONSHIP BETWEEN ATP-BINDING CASSETTE TRANSPORTER A1 …
G Karpouzas, B Papotti, S Ormseth, M Palumbo… - 2023 - ard.bmj.com
Background Cholesterol efflux capacity (CEC) measures the ability of high-density
lipoprotein (HDL) to remove cholesterol from atherosclerotic plaques. It is mediated by …
lipoprotein (HDL) to remove cholesterol from atherosclerotic plaques. It is mediated by …
Macrophage polarisation associated with atherosclerosis differentially affects their capacity to handle lipids
Background and aims Lipid-rich foam cell macrophages drive atherosclerosis via several
mechanisms, including inflammation, lipid uptake, lipid deposition and plaque vulnerability …
mechanisms, including inflammation, lipid uptake, lipid deposition and plaque vulnerability …
Blockade of IL-6 and TNF-α inhibited oxLDL-induced production of MCP-1 via scavenger receptor induction
M Hashizume, M Mihara - European journal of pharmacology, 2012 - Elsevier
In chronic inflammatory diseases, cardiovascular disease risk is increased and is the main
cause of increased mortality. Oxidized LDL (oxLDL) and scavenger receptors participate in …
cause of increased mortality. Oxidized LDL (oxLDL) and scavenger receptors participate in …
[HTML][HTML] Deciphering macrophage phenotypes upon lipid uptake and atherosclerosis
J Lee, JH Choi - Immune Network, 2020 - ncbi.nlm.nih.gov
In the progression of atherosclerosis, macrophages are the key immune cells for foam cell
formation. During hyperlipidemic condition, phagocytic cells such as monocytes and …
formation. During hyperlipidemic condition, phagocytic cells such as monocytes and …
MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases
Low-grade systemic inflammation is often associated with metabolic syndrome, which plays
a critical role in the development of the obesity-associated inflammatory diseases, including …
a critical role in the development of the obesity-associated inflammatory diseases, including …
Toll-like receptor-dependent lipid body formation in macrophage foam cell formation
G Nicolaou, C Erridge - Current opinion in lipidology, 2010 - journals.lww.com
Toll-like receptor-dependent lipid body formation in macroph... : Current Opinion in Lipidology
Toll-like receptor-dependent lipid body formation in macrophage foam cell formation : Current …
Toll-like receptor-dependent lipid body formation in macrophage foam cell formation : Current …
Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms
B Halvorsen, T Wæhre, H Scholz, OP Clausen… - Journal of lipid …, 2005 - ASBMB
Interleukin (IL)-10 may have a therapeutic potential in atherosclerosis, but its mechanisms of
action have not been clarified. Foam cell formation is a key event in atherogenesis, and …
action have not been clarified. Foam cell formation is a key event in atherogenesis, and …
Mechanism and therapeutic potential of macrophages in metabolic and cardiovascular diseases
X Nie, Y Deng, X Tong, F Han - Frontiers in Immunology, 2023 - frontiersin.org
Macrophages have a crucial role in the pathogenesis and progression of metabolic and
cardiovascular diseases, including diabetes, hypertension, atherosclerosis, and heart …
cardiovascular diseases, including diabetes, hypertension, atherosclerosis, and heart …
Mast cells emerge as mediators of atherosclerosis: Special emphasis on IL-37 inhibition
In atherosclerosis lipoproteins stimulate the innate immune response, leading to the release
of inflammatory cytokines and chemokines. Hypercholesterolemia may activate the …
of inflammatory cytokines and chemokines. Hypercholesterolemia may activate the …