Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage.

N Li, C Sioutas, A Cho, D Schmitz… - Environmental …, 2003 - ehp.niehs.nih.gov
The objectives of this study were to determine whether differences in the size and
composition of coarse (2.5-10 micro m), fine (< 2.5 microm), and ultrafine (< 0.1 microm) …

Quinones and aromatic chemical compounds in particulate matter induce mitochondrial dysfunction: implications for ultrafine particle toxicity

T Xia, P Korge, JN Weiss, N Li… - Environmental …, 2004 - ehp.niehs.nih.gov
Particulate pollutants cause adverse health effects through the generation of oxidative
stress. A key question is whether these effects are mediated by the particles or their …

Analysis of air pollution particulate-mediated oxidant stress in alveolar macrophages

CAWGA Imrich, HDYY Ning - Journal of Toxicology and …, 1998 - Taylor & Francis
Adverse health effects of urban air pollution particulates may be attributable to particle
mediated oxidant stress and inflammation. Intracellular oxidant production in normal …

Relationship between redox activity and chemical speciation of size-fractionated particulate matter

L Ntziachristos, JR Froines, AK Cho… - Particle and fibre toxicology, 2007 - Springer
Background Although the mechanisms of airborne particulate matter (PM) related health
effects remain incompletely understood, one emerging hypothesis is that these adverse …

Composition of air pollution particles and oxidative stress in cells, tissues, and living systems

AJ Ghio, MS Carraway, MC Madden - Journal of Toxicology and …, 2012 - Taylor & Francis
Epidemiological studies demonstrated an association between increased levels of ambient
air pollution particles and human morbidity and mortality. Production of oxidants, either …

[HTML][HTML] The combined effects of physicochemical properties of size-fractionated ambient particulate matter on in vitro toxicity in human A549 lung epithelial cells

US Akhtar, N Rastogi, RD McWhinney, B Urch… - Toxicology Reports, 2014 - Elsevier
Epidemiological and toxicological studies have suggested that the health effects associated
with exposure to particulate matter (PM) are related to the different physicochemical …

Murine pulmonary inflammatory responses following instillation of size-fractionated ambient particulate matter

CAJ Dick, P Singh, M Daniels, P Evansky… - Journal of toxicology …, 2003 - Taylor & Francis
The mechanisms for increased cardiopulmonary disease in individuals exposed to
particulate air pollution are associated with fine and ultrafine particles that have a high …

Pulmonary inflammatory response to inhaled ultrafine particles is modified by age, ozone exposure, and bacterial toxin

A CP Elder, R Gelein, J N. Finkelstein, C Cox… - Inhalation …, 2000 - Taylor & Francis
Epidemiological studies demonstrate associations between increasing levels of ambient
particles and morbidity in the elderly with cardiopulmonary disease. Such findings have …

Reactive oxygen species in pulmonary inflammation by ambient particulates

F Tao, B Gonzalez-Flecha, L Kobzik - Free Radical Biology and Medicine, 2003 - Elsevier
Exposure to ambient air pollution particles (PM) has been associated with increased
cardiopulmonary morbidity and mortality, particularly in individuals with pre-existing disease …

Oxidative stress and lipid mediators induced in alveolar macrophages by ultrafine particles

I Beck-Speier, N Dayal, E Karg, KL Maier… - Free Radical Biology …, 2005 - Elsevier
In ambient aerosols, ultrafine particles (UFP) and their agglomerates are considered to be
major factors contributing to adverse health effects. Reactivity of agglomerated UFP of …