The future of peptide‐based drugs
The suite of currently used drugs can be divided into two categories–traditional 'small
molecule'drugs with typical molecular weights of< 500 Da but with oral bioavailability, and …
molecule'drugs with typical molecular weights of< 500 Da but with oral bioavailability, and …
Peptides as 'drugs': the journey so far
S Sachdeva - International journal of peptide research and …, 2017 - Springer
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[HTML][HTML] Peptide therapeutics: current status and future directions
K Fosgerau, T Hoffmann - Drug discovery today, 2015 - Elsevier
Highlights•We provide a SWOT analysis of peptide therapeutics and discuss commercial
aspects.•We comment on emerging peptide technologies and cell-penetrating peptides.• …
aspects.•We comment on emerging peptide technologies and cell-penetrating peptides.• …
Synthetic therapeutic peptides: science and market
P Vlieghe, V Lisowski, J Martinez, M Khrestchatisky - Drug discovery today, 2010 - Elsevier
The decreasing number of approved drugs produced by the pharmaceutical industry, which
has been accompanied by increasing expenses for R&D, demands alternative approaches …
has been accompanied by increasing expenses for R&D, demands alternative approaches …
The current state of peptide drug discovery: back to the future?
A Henninot, JC Collins, JM Nuss - Journal of medicinal chemistry, 2018 - ACS Publications
Over the past decade, peptide drug discovery has experienced a revival of interest and
scientific momentum, as the pharmaceutical industry has come to appreciate the role that …
scientific momentum, as the pharmaceutical industry has come to appreciate the role that …
Therapeutic peptides: current applications and future directions
L Wang, N Wang, W Zhang, X Cheng, Z Yan… - Signal transduction and …, 2022 - nature.com
Peptide drug development has made great progress in the last decade thanks to new
production, modification, and analytic technologies. Peptides have been produced and …
production, modification, and analytic technologies. Peptides have been produced and …
Peptide therapeutics 2.0
BG de la Torre, F Albericio - 2020 - digital.csic.es
Peptide Therapeutics 2.0 Page 1 molecules Editorial Peptide Therapeutics 2.0 Beatriz G. de la
Torre 1,* and Fernando Albericio 2,3,4,* 1 KwaZulu-Natal Research Innovation and …
Torre 1,* and Fernando Albericio 2,3,4,* 1 KwaZulu-Natal Research Innovation and …
Peptide-based drug design: here and now
L Otvos - Peptide-based drug design, 2008 - Springer
After many years of stagnation, peptide therapeutics once again became the focus of
innovative drug development efforts backed up by venture funds and biotechnology …
innovative drug development efforts backed up by venture funds and biotechnology …
Therapeutic peptides
F Albericio, HG Kruger - Future medicinal chemistry, 2012 - Taylor & Francis
The analysis of these peptides by therapeutic categories is an indication of the versatility of
peptides to tackle a large number of biochemical transgressions. Thus, boceprevir and …
peptides to tackle a large number of biochemical transgressions. Thus, boceprevir and …
Peptides as drugs: is there a market?
A Loffet - Journal of peptide science: an official publication of …, 2002 - Wiley Online Library
The first synthetic peptide was prepared by Emil Fischer a century ago, but the medicinal
use of synthetic peptides started after the Second World War, and only when peptides could …
use of synthetic peptides started after the Second World War, and only when peptides could …