Asthmatic individuals appear to be particularly sensitive to the effects of certain air pollutants-
including ozone (O3), an oxidant ambient air pollutant-for reasons that are poorly …

The effects of ozone (O3) on airway epithelia, inflammation, and expression of inflammatory
stimuli were investigated to delineate the mechanisms of inflam matory reactions relevant to …

Acute exposure of animals and humans to ozone results in decrements in lung function,
development of airway hyperreactivity, inflammation, edema, damage to pulmonary cells …

Exposure to ozone at levels near the National Ambient Air Quality Standard causes
respiratory symptoms, changes in lung function, and airway inflammation. Although ozone …

To study whether the individual inflammatory response to ozone was reproducible, dose-
dependent, and time-dependent, we performed two exposures to 250 ppb ozone, one to 125 …

Abstract Ozone (O3), a criterion air pollutant produced as a product of internal combustion,
generates increased inflammation, lung permeability, and airway hyperreactivity when …

While acute exposures to ozone (O 3) can alter airway responsiveness, effects from long-
term exposures at low concentrations are less clear. This study assessed whether such …

We investigated the cellular and molecular effects of ozone exposure in Cynomolgus
monkeys. Thirty-six Cynomolgus monkeys were exposed to single or repeat ozone …

We demonstrated previously that C57BL/6J (B6) inbred mice are susceptible and C3H/HeJ
(C3) mice are resistant to airway inflammation that is induced by acute (3 h) exposure to 2 …

The present study was designed to assess the effects of repeated subacute ozone (O3)
exposure on pulmonary inflammation and ventilation in two inbred strains of mice …